Tacrolimus Accord

This medicine treats moderate to severe eczema by calming the skin's immune response to reduce inflammation and itching.

Form
voide
Strength
0.03 %
Active Ingredient
Tacrolimus monohydrate
Manufacturer
Accord Healthcare B.V.

How to Use

Dosage

For children (2+), apply 0.03% cream twice daily for up to 3 weeks, then once daily until eczema clears. For adults (16+), usually start with 0.1% cream twice daily until eczema clears; your doctor may adjust this. For maintenance, apply twice a week.

Method

Apply a thin layer to the affected skin area. You can use it on most body parts, including your face and neck. Avoid getting it in your nose, mouth, or eyes; if it happens, wipe it off and rinse with water. Do not cover the treated area with bandages. Wash your hands after applying, unless your hands are also being treated. Make sure your skin is completely dry after bathing or showering before applying the cream. Do not bathe, shower, or swim immediately after applying the cream as water can wash it off.

Important

Do not apply more than twice a day during the active treatment phase.

Possible Side Effects

COMMON
  • Burning sensation
  • Itching
  • Redness
  • Warmth
  • Pain
  • Increased skin sensitivity (especially to heat and cold)
  • Tingling or creeping sensation in the skin
  • Rash
  • Local skin infections (e.g., hair follicle inflammation, cold sores)
  • Facial redness or skin irritation after drinking alcohol
RARE
  • Acne
  • Impetigo (a bacterial skin infection causing blisters/sores)
  • Rosacea (facial redness)
  • Rosacea-like skin inflammation
  • Lentigo (flat brown spots on the skin)
  • Swelling in the treated area
  • Herpes infection in the eye

Important Warnings

  • Do not use if you are allergic to tacrolimus, any other ingredient in Tacrolimus Accord, or macrolide antibiotics (e.g., azithromycin).
  • Talk to your doctor if you have liver problems, skin cancer, a weakened immune system, swollen lymph nodes, or certain hereditary skin diseases (like Netherton's syndrome).
  • Do not apply the cream to inflamed skin lesions or if you notice any changes in your skin's appearance; tell your doctor immediately.
  • Avoid long exposure to sunlight and artificial UV light (like tanning beds). Use sunscreen and protective clothing when outdoors. Do not use with light therapy.
  • This cream is not approved for children under 2 years of age.
Show 2 more warnings
  • Wait at least two hours between applying Tacrolimus Accord and any moisturizers or lotions. Drinking alcohol may cause facial flushing or skin irritation.
  • If you are pregnant, breastfeeding, or planning to have a baby, talk to your doctor or pharmacist before using this medicine.