Sunitinib Viatris
Sunitinib Viatris is a cancer medicine that stops cancer cells from growing and spreading by blocking certain proteins.
Form
kapseli, kova
Strength
50 mg
Active Ingredient
Sunitinib
Manufacturer
Viatris Limited
How to Use
Dosage
For stomach or kidney cancer: usually take 50 mg once a day for 4 weeks, then stop for 2 weeks. For pancreatic cancer: take 37.5 mg once a day without breaks.
Method
You can take the capsules with or without food.
Important
The highest daily dose is usually 50 mg for certain cancers or 37.5 mg for others.
Possible Side Effects
COMMON
- •Lower blood cell counts
- •Trouble breathing
- •High blood pressure
- •Feeling very tired or weak
- •Swelling due to fluid buildup
- •Mouth pain/soreness/dryness, changes in taste
- •Upset stomach, feeling sick, throwing up, diarrhea, constipation, stomach pain, not wanting to eat
- •Underactive thyroid
- •Dizziness
- •Headache
- •Nosebleeds
- •Back, joint, and limb pain
- •Yellow/darkened skin, changes in hair color, rash, dry skin
- •Cough
- •Fever
- •Trouble sleeping
- •Blood clots
- •Reduced blood flow to heart muscle, chest pain
- •Weaker heart pumping
- •Fluid around lungs
- •Infections
- •Low blood sugar
- •Protein in urine
- •Flu-like symptoms
- •Abnormal blood tests (pancreas/liver)
- •High uric acid in blood
- •Hemorrhoids, rectal pain, bleeding gums, trouble swallowing
- •Burning tongue, gut inflammation, gas
- •Losing weight
- •Muscle/bone pain, weak muscles, muscle cramps
- •Dry/blocked nose
- •Watery eyes
- •Numb skin, itching, peeling skin, skin inflammation, blisters, acne, nail discoloration, hair loss
- •Strange feelings in arms/legs
- •Changed touch sensitivity
- •Heartburn
- •Dehydration
- •Hot flashes
- •Discolored urine
- •Depression
- •Chills
RARE
- •Life-threatening soft tissue infection
- •Stroke
- •Heart attack (due to poor blood flow)
- •Abnormal heart rhythm
- •Fluid around the heart
- •Liver failure or inflammation
- •Pancreatitis-related stomach pain
- •Tumor breakdown leading to a hole in the gut
- •Gallbladder inflammation
- •Abnormal passage/fistula
- •Mouth, tooth, and/or jaw pain, swelling/sores, numbness, loose teeth (may be jaw bone damage)
- •Overactive thyroid
- •Wound healing problems after surgery
- •High muscle enzyme in blood
- •Severe allergic reaction (e.g., rash, swelling, breathing trouble)
- •Colon inflammation (colitis)
- •Severe skin/mucous reactions
- •Tumor lysis syndrome (metabolic issues during cancer treatment)
- •Abnormal muscle breakdown (rhabdomyolysis)
- •Abnormal brain changes (headache, confusion, seizures, vision loss)
- •Painful skin ulcers (pyoderma gangrenosum)
- •Thyroid inflammation
- •Damage to small blood vessels (TMA)
- •Enlarged/weakened blood vessel or tear (aneurysm)
- •Lack of energy, confusion, drowsiness, unconsciousness/coma (signs of brain toxicity)
Important Warnings
- This medicine can raise your blood pressure. Your doctor will check it regularly.
- You might bleed or bruise more easily. Tell your doctor if you have any bleeding.
- This medicine can cause heart problems, such as tiredness, shortness of breath, or swollen feet.
- Call your doctor right away if you have signs of a blood clot, such as chest pain or trouble speaking.
- Tell your doctor if you have or have had enlarged or damaged blood vessels.
Show 13 more warnings
- This medicine can affect your thyroid. Your doctor will monitor it with blood tests.
- Tell your doctor if you have upper stomach pain, nausea, vomiting, or fever.
- Tell your doctor if your skin or the whites of your eyes turn yellow, or if your urine gets dark.
- Your doctor will check how well your kidneys are working.
- This medicine can slow wound healing. Tell your doctor if you have had or will have surgery.
- See your dentist before starting treatment, and tell your doctor if you have mouth, tooth, or jaw pain.
- Contact your doctor right away if you get a severe rash, skin sores, or a fast-spreading skin infection.
- Tell your doctor if you have had seizures.
- If you have diabetes, your blood sugar needs to be closely watched, and your doctor may adjust your diabetes medicine.
- Do not drink grapefruit juice while taking this medicine.
- Do not use this medicine if you are pregnant or breastfeeding. Talk to your doctor about birth control.
- Be careful when driving or using machines if you feel dizzy or tired.
- Do not take this medicine if you are allergic to sunitinib or any other ingredients.