Spironolactone Orion
This medicine (spironolactone) helps your body get rid of extra fluid by making you pee more, without losing potassium.
How to Use
Dosage
Your doctor will tell you the right dose. For adults, it's usually 25-100 mg daily, but can be up to 400 mg for short periods or specific conditions. For children, the doctor decides based on weight and illness.
Method
Take the tablet with a glass of water or other drink, with food. You can take your daily dose once a day or split it into two doses. Try to take it at the same time each day to help it work best and to remember it.
The maximum daily dose for severe swelling or specific conditions is typically 400 mg for a short period.
Possible Side Effects
- •Headache
- •Digestive problems
- •Nausea
- •Diarrhea
- •Vomiting
- •Dry skin
- •Drowsiness
- •Breast growth in men
- •Breast tenderness
- •Menstrual cycle disturbances
- •Impotence
- •Too much potassium or too little sodium in the blood
- •Confusion
- •Strange sensations (e.g., tingling)
- •Skin rashes
- •Itching
- •Hives (nettle rash)
- •Leg cramps
- •Changes in blood creatinine or renin levels
- •Dehydration
- •Apathy (lack of interest or initiative)
- •Changes in sexual desire
- •Dizziness
- •Kidney failure
- •Decreased white blood cells or platelets
- •Impaired liver function
- •Hair loss
- •Increased body hair
- •Benign breast tumors
- •Severe skin reactions (like TEN, SJS, DRESS, Pemphigoid)
Important Warnings
- Do not take this medicine if you are allergic to spironolactone or any other ingredient.
- Do not take this medicine if you have severe kidney problems or if your body stops making urine.
- Do not take if you have very high potassium or very low sodium levels in your blood.
- Tell your doctor if you have liver or kidney problems, diabetes with kidney issues, or stomach ulcers.
- Avoid foods and supplements high in potassium, as this can lead to dangerously high potassium levels in your blood.
Show 2 more warnings
- This medicine is not for children with moderate to severe kidney disease.
- If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Reduce the dose in moderately severe renal impairment. Do not use in severe renal impairment. Consider risk of hyperkalaemia.. (updated 19.5.2025)