Spironolactone Orion
This medicine, Spironolactone Orion, helps your body get rid of extra fluid by making you urinate more, but unlike other similar medicines, it does not make you lose potassium.
How to Use
Dosage
Your doctor will tell you how much to take; typical daily doses for adults are 25-100 mg, but it can be adjusted based on your condition.
Method
Take this medicine with food and a glass of water, either all at once or split into two doses, preferably at the same time each day.
For severe swelling, the maximum daily dose can be up to 400 mg for a short period, as prescribed by your doctor.
Possible Side Effects
- •headache
- •stomach problems
- •nausea
- •diarrhea
- •vomiting
- •dry skin
- •drowsiness
- •breast enlargement in men
- •breast tenderness
- •menstrual cycle changes
- •impotence
- •very high or very low blood potassium/sodium levels
- •confusion
- •strange sensations (tingling, numbness)
- •skin rashes
- •itching
- •hives
- •leg cramps
- •dehydration
- •apathy (lack of interest)
- •changes in sexual drive
- •dizziness
- •kidney problems (worsening)
- •reduced white blood cells or platelets
- •liver problems (worsening)
- •hair loss
- •increased body hair
- •non-cancerous breast lumps
- •severe skin reactions (toxic epidermal necrolysis, Stevens-Johnson syndrome, DRESS, pemphigoid)
Important Warnings
- Do not take this medicine if you are allergic to spironolactone or any other ingredient in it.
- Do not take this medicine if you have severe kidney problems or if your kidneys have stopped making urine.
- Do not take this medicine if you have very high levels of potassium or very low levels of sodium in your blood.
- Do not take this medicine if you have a sudden problem with your adrenal glands (Addison's crisis) or a rare blood disorder called porphyria.
- Tell your doctor if you are taking other medicines, potassium supplements, or eating foods high in potassium, as this can lead to dangerous potassium levels in your blood. Symptoms include muscle cramps, irregular heartbeat, diarrhea, nausea, dizziness, and headache.
Show 2 more warnings
- Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine is generally not recommended during breastfeeding.
- This medicine can make you feel dizzy or tired, especially when you start taking it or when your dose changes. Do not drive or operate machines until you know how it affects you.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Reduce the dose in moderately severe renal impairment. Do not use in severe renal impairment. Consider risk of hyperkalaemia.. (updated 19.5.2025)