Somac
Somac reduces stomach acid to treat acid-related diseases like ulcers and reflux.
Form
injektiokuiva-aine, liuosta varten
Strength
40 mg
Active Ingredient
Pantoprazole sodium sesquihydrate
Manufacturer
Takeda GmbH
How to Use
Dosage
For most conditions, the usual dose is one 40 mg vial per day. For Zollinger-Ellison syndrome, it's two 40 mg vials (80 mg) per day. If you have severe liver problems, the dose is one half vial (20 mg) per day.
Method
A nurse or doctor will give you your daily dose as an injection into a vein over 2-15 minutes. This medicine is given intravenously when tablets are not suitable; you will switch to tablets as soon as your doctor thinks it's possible.
Important
The maximum daily dose for most patients is 160 mg (four 40 mg vials), though your doctor might adjust this. If you have severe liver problems, the maximum daily dose is 20 mg (half a 40 mg vial).
Possible Side Effects
COMMON
- •Inflammation of the vein wall and blood clot at the injection site.
- •Benign stomach polyps.
RARE
- •Headache.
- •Dizziness.
- •Diarrhea.
- •Nausea.
- •Vomiting.
- •Stomach swelling and gas.
- •Constipation.
- •Dry mouth.
- •Stomach pain and discomfort.
- •Rash, skin eruption.
- •Itching.
- •Feeling weak, tired or generally unwell.
- •Sleep problems.
- •Bone fractures (hip, wrist, spine).
- •Altered or absent taste.
- •Vision problems (blurred vision).
- •Joint pain.
- •Muscle pain.
- •Weight changes.
- •Increased body temperature, high fever.
- •Swelling in limbs (peripheral edema).
- •General allergic reactions.
- •Depression.
- •Enlarged breasts in men.
- •Disorientation.
- •Hallucinations.
- •Confusion (especially if you've had these symptoms before).
- •Tingling, prickling, burning feeling or numbness.
- •Inflammation of the large intestine causing persistent watery diarrhea.
- •Severe allergic reactions: swelling of the tongue and/or throat, difficulty swallowing, hives, breathing difficulties, allergic facial swelling, severe dizziness with rapid heartbeat and heavy sweating.
- •Severe skin problems: blisters on the skin, rapid worsening of general condition, superficial sores (with slight bleeding) in eyes, nose, mouth/lips or genitals, or skin sensitivity/rash especially on light/sun-exposed areas. You may also have joint pain and flu-like symptoms (fever, swollen lymph nodes); blood tests may show changes in white blood cell counts or liver enzyme values. Reddish, raised or round target-like lesions on the body (often with a blister in the middle), peeling skin, sores in mouth, throat, nose, genitals and eyes. These severe rashes can be preceded by fever and flu-like symptoms (Stevens-Johnson syndrome, toxic epidermal necrolysis). Widespread rash, high body temperature and enlarged lymph nodes (DRESS syndrome).
- •Other serious conditions: yellowing of skin or whites of eyes (severe liver cell damage, jaundice) or fever, rash, and enlarged kidneys, sometimes with pain during urination and lower back pain (severe kidney inflammation) that can lead to kidney failure.
- •Blood test findings: Increased liver enzyme values.
- •Increased bilirubin, higher blood fat levels, high fever with severe decrease in white blood cells (granulocytes).
- •Decrease in platelets (easier bleeding/bruising), decrease in white blood cells (more infections), simultaneous decrease in red/white blood cells and platelets.
- •Low sodium, magnesium, calcium or potassium levels in blood.
Important Warnings
- If you have severe liver problems or a history of them, tell your doctor. They will monitor your liver enzymes, and treatment might need to be stopped if enzyme levels rise.
- If you are taking HIV protease inhibitors (e.g., atazanavir), tell your doctor, as they might need to adjust your treatment.
- Long-term use (over a year) of Somac may slightly increase the risk of hip, wrist, or spine fractures. Tell your doctor if you have osteoporosis or are at risk.
- If you use Somac for more than three months, your blood magnesium levels might drop, causing fatigue, muscle cramps, confusion, dizziness, or fast heartbeat. Contact your doctor immediately if you experience these symptoms.
- If you get a rash, especially on sun-exposed areas, tell your doctor as soon as possible. You might need to stop Somac. Also, report any joint pain or other symptoms. Severe skin reactions (e.g., Stevens-Johnson syndrome, DRESS) have been reported; stop use and seek medical attention immediately if you notice severe skin symptoms.
Show 2 more warnings
- If you are having a specific blood test (chromogranin A), tell your doctor.
- Seek immediate medical attention if you experience: unexplained weight loss, repeated vomiting (especially blood that looks like coffee grounds), black tarry stools, difficulty swallowing or pain, paleness, weakness (anemia), chest pain, abdominal pain, or severe/persistent diarrhea. These could be signs of a more serious condition.