Sitagliptin/Metformin Sandoz
This medicine helps adults with type 2 diabetes control their blood sugar by increasing insulin after meals and reducing sugar made by the body, alongside diet and exercise.
Form
tabletti, kalvopäällysteinen
Strength
50 mg / 1000 mg
Active Ingredient
Metformin hydrochloride
Manufacturer
Sandoz A/S
How to Use
Dosage
One tablet, twice daily.
Method
Take orally with meals to help prevent stomach upset.
Important
Do not exceed the dose prescribed by your doctor, usually one tablet twice daily.
Possible Side Effects
COMMON
- •Low blood sugar
- •Nausea
- •Vomiting
- •Diarrhea
- •Abdominal pain (stomach ache)
- •Flatulence (gas)
- •Constipation
- •Loss of appetite
- •Headache
- •Upper respiratory infection (cold symptoms)
- •Stuffy or runny nose and sore throat
- •Osteoarthritis
- •Arm and leg pain
- •Metallic taste in mouth
- •Low vitamin B12 levels (symptoms: extreme tiredness, sore/red tongue, tingling, pale/yellow skin)
- •Swelling of hands or feet
RARE
- •Drowsiness
- •Dizziness
- •Itching
- •Dry mouth
- •Decreased platelet count
- •Kidney problems (sometimes needing dialysis)
- •Joint pain
- •Muscle pain
- •Back pain
- •Interstitial lung disease
- •Bullous pemphigoid (skin blisters)
- •Hepatitis (liver inflammation)
- •Hives (nettle rash)
- •Skin redness (rash)
Important Warnings
- Do not take this medicine if you are allergic to sitagliptin, metformin, or any other ingredients.
- Do not take if you have severe kidney or liver problems, or Type 1 diabetes.
- Do not take if your diabetes is poorly controlled, especially if you have very high blood sugar, nausea, vomiting, diarrhea, rapid weight loss, lactic acidosis, or ketoacidosis.
- Avoid heavy alcohol use.
- Do not take if you are pregnant or breastfeeding.
Show 5 more warnings
- Stop taking immediately and seek urgent medical help if you get severe stomach pain (possibly spreading to your back, with or without nausea/vomiting), as this could be a sign of pancreatitis (inflammation of the pancreas).
- Stop taking immediately and go to the nearest hospital if you get symptoms of lactic acidosis (vomiting, severe stomach pain, muscle cramps, feeling very tired, difficulty breathing, feeling cold, or a slow heart rate), as this is a serious medical emergency.
- Stop taking immediately and contact your doctor if you have a severe allergic reaction (rash, hives, skin blisters, or swelling of your face, lips, tongue, or throat causing breathing or swallowing problems).
- Inform your doctor if you are having surgery, medical imaging with contrast dye, or if you become dehydrated, as you may need to stop this medicine temporarily.
- If you are taking this medicine with insulin or a sulfonylurea, your doctor may adjust your dose to prevent low blood sugar.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Do not use in severe renal impairment or tissue hypoxia. May reduce the absorption of vitamin B12. Consider risk of lactic acidosis. The drug should be paused during fever, gastroenteritis or dehydration, and before surgery or imaging with a contrast agent. (updated 20.5.2024)