Sitagliptin/Metformin ratiopharm
This medicine helps control blood sugar levels in adults with type 2 diabetes by increasing insulin after meals and reducing the body's sugar production.
Form
tabletti, kalvopäällysteinen
Strength
50 mg / 1000 mg
Active Ingredient
Metformin hydrochloride
Manufacturer
ratiopharm GmbH
How to Use
Dosage
One tablet, twice a day.
Method
Take orally with meals to reduce stomach upset.
Important
Follow your doctor's instructions; usually two tablets per day.
Possible Side Effects
COMMON
- •Low blood sugar
- •Nausea
- •Vomiting
- •Diarrhea
- •Stomach pain
- •Flatulence (gas)
- •Constipation
- •Headache
- •Upper respiratory tract infection
- •Stuffy or runny nose and sore throat
- •Osteoarthritis (joint pain caused by wear and tear)
- •Pain in arms or legs
- •Swelling of hands or feet
- •Loss of appetite
- •Metallic taste in mouth
- •Reduced or low vitamin B12 levels, with symptoms like extreme tiredness, sore or red tongue, tingling, or pale/yellow skin.
RARE
- •Drowsiness
- •Dizziness
- •Itching
- •Dry mouth
- •Reduced number of platelets (which help blood clot)
- •Kidney problems
- •General joint pain
- •Muscle pain
- •Back pain
- •Interstitial lung disease (a type of lung problem)
- •Hepatitis (liver inflammation)
- •Hives
- •Red skin or rash
Important Warnings
- Do not take if you are allergic to sitagliptin, metformin, or any other ingredient in this medicine.
- Do not take if you have severe kidney or liver problems.
- Do not take if your diabetes is poorly controlled with very high blood sugar, vomiting, diarrhea, or rapid weight loss.
- Do not take if you have a severe infection or are dehydrated.
- Do not take if you recently had a heart attack or have severe circulatory or breathing problems.
Show 6 more warnings
- Do not take if you drink a lot of alcohol (regularly or occasionally).
- Do not take if you are pregnant or breastfeeding.
- Stop taking this medicine and call your doctor immediately if you have severe and ongoing stomach pain, with or without nausea and vomiting, as these can be signs of pancreas inflammation (pancreatitis).
- Stop taking this medicine and contact your doctor immediately or go to the nearest hospital if you have symptoms of lactic acidosis, a very rare but serious side effect. Symptoms include vomiting, stomach pain, muscle cramps, feeling very tired, trouble breathing, lower body temperature, and slow heartbeat.
- Stop taking this medicine and contact your doctor immediately if you get blisters on your skin, as this could be a sign of a rare skin condition (bullous pemphigoid).
- You may need to stop this medicine temporarily if you have an X-ray with an injected dye, or if you are having major surgery. Your doctor will tell you when to stop and restart.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Do not use in severe renal impairment or tissue hypoxia. May reduce the absorption of vitamin B12. Consider risk of lactic acidosis. The drug should be paused during fever, gastroenteritis or dehydration, and before surgery or imaging with a contrast agent. (updated 20.5.2024)