Sitagliptin/Metformin Krka
This medicine helps adults with type 2 diabetes control their blood sugar by increasing insulin after meals and reducing sugar made by the body, working with diet and exercise.
Form
tabletti, kalvopäällysteinen
Strength
50 mg / 1000 mg
Active Ingredient
Sitagliptin
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
One tablet.
Method
Take by mouth twice a day with meals to reduce stomach upset.
Important
Your doctor will decide your dose, and may adjust it to control your blood sugar.
Possible Side Effects
COMMON
- •Low blood sugar
- •Nausea
- •Vomiting
- •Diarrhea
- •Stomach pain
- •Flatulence
- •Constipation
- •Headache
- •Upper respiratory infection
- •Stuffy or runny nose and sore throat
- •Joint pain
- •Arm or leg pain
- •Loss of appetite
- •Metallic taste in mouth
- •Drowsiness
RARE
- •Decreased number of platelets (cells that help blood clot)
- •Kidney problems (sometimes requiring dialysis)
- •Muscle pain
- •Back pain
- •Interstitial lung disease (a type of lung inflammation)
- •Blisters on the skin (a skin condition called bullous pemphigoid)
- •Liver inflammation (hepatitis)
- •Hives
- •Red skin rash
- •Itching
- •Low Vitamin B12 levels in blood
Important Warnings
- Stop taking this medicine and call your doctor right away if you have a serious allergic reaction, like a rash, hives, blisters, or swelling of your face, lips, tongue, or throat.
- Stop taking this medicine and call your doctor right away if you have severe and ongoing stomach pain that spreads to your back, with or without feeling sick or throwing up. These could be signs of an inflamed pancreas.
- This medicine can cause a very rare but serious problem called lactic acidosis. Stop taking this medicine and go to the nearest hospital right away if you have symptoms like feeling cold or unwell, severe nausea or throwing up, stomach pain, muscle cramps, unexplained weight loss, or fast breathing.
- Do not take this medicine if you have severe kidney problems. Your doctor will check your kidneys regularly.
- Do not take this medicine if you have a severe infection or are very dehydrated (lack of fluids).
Show 5 more warnings
- If you are having an X-ray or scan with a special dye (contrast medium), you must stop taking this medicine for a few days before and after the procedure, as instructed by your doctor.
- Do not take this medicine if you have liver problems.
- Avoid drinking too much alcohol while taking this medicine, as it can increase the risk of lactic acidosis.
- Do not take this medicine if you are pregnant or breastfeeding.
- If you get blisters on your skin, tell your doctor. They might ask you to stop this medicine.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Do not use in severe renal impairment or tissue hypoxia. May reduce the absorption of vitamin B12. Consider risk of lactic acidosis. The drug should be paused during fever, gastroenteritis or dehydration, and before surgery or imaging with a contrast agent. (updated 20.5.2024)