Sitagliptin/Metformin Krka
Sitagliptin/Metformin Krka helps lower blood sugar and manage type 2 diabetes by increasing insulin and decreasing the body's sugar production.
Form
tabletti, kalvopäällysteinen
Strength
50 mg / 850 mg
Active Ingredient
Sitagliptin
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
One tablet twice a day, as prescribed by your doctor.
Method
Take by mouth with meals to help prevent stomach upset.
Important
The maximum daily dose is determined by your doctor, typically two tablets per day.
Possible Side Effects
COMMON
- •Low blood sugar
- •Nausea
- •Vomiting
- •Diarrhea
- •Stomach pain
- •Flatulence (gas)
- •Constipation
- •Loss of appetite
- •Upper respiratory tract infection
- •Stuffy or runny nose and sore throat
- •Headache
- •Osteoarthritis
- •Arm and leg pain
- •Swelling of hands or feet
- •Metallic taste in mouth
- •Low vitamin B12 levels (tiredness, sore red tongue, tingling, pale or yellow skin)
RARE
- •Drowsiness
- •Dizziness
- •Itching
- •Decreased number of platelets
- •Kidney problems (sometimes needing dialysis)
- •Joint pain
- •Muscle pain
- •Back pain
- •Interstitial lung disease (a type of lung problem)
- •Skin blisters (bullous pemphigoid)
- •Dry mouth
- •Hepatitis (liver inflammation)
- •Hives
- •Skin redness (rash)
Important Warnings
- Do not take if you are allergic to sitagliptin, metformin, or any other ingredients.
- Do not take if you have severe kidney or liver disease, or uncontrolled type 2 diabetes (high blood sugar, nausea, vomiting, diarrhea, rapid weight loss, or ketoacidosis).
- Stop taking immediately and contact your doctor or nearest hospital if you have symptoms of lactic acidosis (e.g., severe tiredness, stomach pain, muscle cramps, trouble breathing, coldness, slow heart rate), as this is a serious condition.
- Tell your doctor if you are dehydrated (due to severe vomiting, diarrhea, fever, or not drinking enough), or if you are having surgery or a medical scan with contrast dye, as you may need to stop the medicine temporarily.
- Stop taking and contact your doctor immediately if you have severe stomach pain (could be pancreatitis) or skin blisters (bullous pemphigoid).
Show 2 more warnings
- Do not take if you are pregnant, breastfeeding, or drink a lot of alcohol.
- This medicine is not for type 1 diabetes.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Do not use in severe renal impairment or tissue hypoxia. May reduce the absorption of vitamin B12. Consider risk of lactic acidosis. The drug should be paused during fever, gastroenteritis or dehydration, and before surgery or imaging with a contrast agent. (updated 20.5.2024)