Sitagliptin/Metformin Glenmark
This medicine helps adults with type 2 diabetes control their blood sugar by increasing insulin after meals and reducing sugar made by the body.
Form
tabletti, kalvopäällysteinen
Strength
50 mg / 850 mg
Active Ingredient
Sitagliptin hydrochloride monohydrate
Manufacturer
Glenmark Arzneimittel GmbH
How to Use
Dosage
Take one tablet.
Method
Take by mouth twice a day, with meals, to help prevent stomach upset.
Important
Your doctor will decide the maximum daily dose for you, possibly adjusting it based on your kidney function.
Possible Side Effects
COMMON
- •Low blood sugar
- •Nausea
- •Vomiting
- •Diarrhea
- •Flatulence (gas)
- •Stomach pain
- •Loss of appetite
- •Headache
- •Upper respiratory tract infection
- •Stuffy or runny nose and sore throat
- •Joint pain (osteoarthritis)
- •Pain in arms or legs
- •Constipation
- •Swollen hands and feet
- •Metallic taste in mouth
- •Low vitamin B12 levels (may cause extreme tiredness, sore or red tongue, tingling or numbness, pale or yellow skin)
RARE
- •Drowsiness
- •Dizziness
- •Itching
- •Dry mouth
- •Decreased number of platelets (which help blood clot)
- •Liver problems (hepatitis)
- •Kidney problems (in some cases requiring artificial kidney treatment)
- •Muscle pain
- •Back pain
- •Interstitial lung disease (a type of lung problem)
- •Blisters on the skin (bullous pemphigoid)
Important Warnings
- Do not take if you are allergic to sitagliptin, metformin, or any other ingredient in this medicine.
- Do not take if you have severe kidney problems.
- Do not take if your diabetes is poorly controlled, or if you have lactic acidosis or ketoacidosis. Symptoms include stomach pain, rapid breathing, drowsiness, or a fruity smell on your breath.
- Do not take if you have a severe infection or are dehydrated.
- Stop taking this medicine before and for some days after an X-ray using contrast dye injected into your veins, as advised by your doctor.
Show 6 more warnings
- Do not take if you recently had a heart attack or have severe circulatory problems (like shock) or breathing difficulties.
- Do not take if you have liver problems.
- Do not take if you drink a lot of alcohol (daily or occasionally).
- Do not take if you are pregnant or breastfeeding, or if you plan to become pregnant.
- Stop taking and contact your doctor if you experience severe, ongoing stomach pain that may spread to your back, with or without nausea and vomiting, as this may be a sign of pancreatitis (inflammation of the pancreas).
- If you get a severe allergic reaction (rash, hives, skin blisters, swelling of face, lips, tongue, or throat causing breathing/swallowing difficulties), stop taking this medicine and contact your doctor immediately.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Do not use in severe renal impairment or tissue hypoxia. May reduce the absorption of vitamin B12. Consider risk of lactic acidosis. The drug should be paused during fever, gastroenteritis or dehydration, and before surgery or imaging with a contrast agent. (updated 20.5.2024)