Simvastatin Ratiopharm
Simvastatin ratiopharm lowers 'bad' cholesterol (LDL) and triglycerides in your blood, and increases 'good' cholesterol (HDL).
How to Use
Dosage
Your doctor will decide your dose, usually 5 mg, 10 mg, 20 mg, 40 mg, or up to 80 mg of simvastatin once daily; for children (10-17 years), the usual starting dose is 10 mg in the evening.
Method
Take your tablet in the evening, with or without food; if you also take a bile acid binding medicine, take Simvastatin ratiopharm at least 2 hours before or 4 hours after that medicine.
The maximum daily dose for adults is 80 mg; for children and adolescents, the maximum daily dose is 40 mg.
Possible Side Effects
- •Unexplained muscle pain, tenderness, weakness, or cramps; this can be serious and, in rare cases, lead to muscle breakdown, kidney damage, or death.
- •Severe allergic reactions, including swelling of the face, tongue, or throat which can cause difficulty breathing, severe muscle pain, skin rashes, or joint pain.
- •Liver problems, which may include yellow skin or eyes, itching, dark urine, pale stools, tiredness, or loss of appetite.
- •Inflammation of the pancreas, causing severe stomach pain.
- •A severe allergic reaction (anaphylaxis) that can cause breathing difficulties or dizziness.
- •Gynecomastia (breast enlargement in men).
- •Low red blood cell count (anemia).
- •Numbness, weakness, headache, dizziness, or tingling in the arms and legs.
- •Blurred vision or impaired vision.
- •Stomach pain, constipation, gas, indigestion, diarrhea, nausea, or vomiting.
- •Skin rash, itching, or hair loss.
- •General weakness.
- •Trouble sleeping, nightmares, memory loss, confusion, or depression.
- •Erection problems.
- •Tendon problems, sometimes including rupture.
- •Persistent muscle weakness, potentially including myasthenia gravis or ocular myasthenia.
- •Breathing problems, such as persistent cough, shortness of breath, or fever.
- •Diabetes, more likely if you have high blood sugar, high blood fat, are overweight, and have high blood pressure.
Important Warnings
- Do not take if you are allergic to simvastatin or any other ingredient in this medicine.
- Do not take if you have liver disease, are pregnant, or breastfeeding.
- Avoid certain other medicines; tell your doctor about all medicines you are taking, as some should not be used with Simvastatin ratiopharm.
- Do not take more than 40 mg of Simvastatin ratiopharm if you are also taking lomitapide.
- Stop taking this medicine and contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, as this could be a sign of a serious muscle problem.
Show 2 more warnings
- If you need to take fusidic acid for a bacterial infection, you must temporarily stop taking this medicine.
- Avoid drinking grapefruit juice while taking this medicine.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Reduce the dose in severe renal impairment. Possible adverse effects include muscle pain and muscular weakness. Consider potential interactions. Avoid grapefruit. (updated 17.4.2023)