Simvastatin Krka
Simvastatin Krka tablets help lower 'bad' cholesterol and triglycerides in your blood, and increase 'good' cholesterol.
Form
tabletti, kalvopäällysteinen
Strength
40 mg
Active Ingredient
Simvastatin
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
Your doctor will determine your dose. Adults usually start with 10-40 mg daily, and children (10-17 years) start with 10 mg in the evening.
Method
Take one tablet once a day in the evening, with or without food.
Important
Do not take more than 80 mg per day.
Possible Side Effects
RARE
- •Muscle pain, tenderness, weakness, or cramps.
- •Swelling of the face, tongue, or throat, which can cause breathing problems (allergic reaction).
- •Severe muscle pain, often in the shoulders and hips.
- •Rash with weakness in arm, leg, and neck muscles.
- •Joint pain or inflammation.
- •Inflammation of blood vessels (vasculitis).
- •Unusual bruising, rash, and swelling, hives, sensitivity to light, fever, redness.
- •Shortness of breath and a general feeling of illness.
- •Lupus-like symptoms (rash, joint pain, blood changes).
- •Liver inflammation with yellowing of the skin or eyes, itching, dark urine, pale stools, tiredness, weakness, or loss of appetite.
- •Pancreatitis (inflammation of the pancreas), often with severe stomach pain.
- •Low red blood cell count (anemia).
- •Numbness or weakness in hands and feet.
- •Headache, tingling sensation, dizziness.
- •Blurred vision and impaired eyesight.
- •Digestive problems (abdominal pain, constipation, gas, indigestion, diarrhea, nausea, vomiting).
- •Rash, itching, and hair loss.
- •Weakness.
- •Insomnia (difficulty sleeping).
- •Memory problems, memory loss, confusion.
- •Severe allergic reaction with breathing problems or dizziness (anaphylaxis).
- •Rash or sores in the mouth (lichenoid drug eruption).
- •Muscle rupture.
- •Gynecomastia (breast enlargement in men).
- •Erectile dysfunction.
- •Depression.
- •Lung inflammation causing breathing difficulties, including persistent cough and/or shortness of breath or fever.
- •Tendon problems, sometimes with tendon rupture.
- •Myasthenia gravis (a disease causing general muscle weakness, sometimes affecting breathing muscles).
- •Ocular myasthenia (a disease causing weakness in eye muscles).
- •Sleep problems, including nightmares.
- •Sexual problems.
- •Diabetes (more likely if you have high blood sugar, high blood fats, are overweight, or have high blood pressure).
- •Persistent muscle pain, tenderness, or weakness that may not go away after stopping the medicine.
Important Warnings
- Do not take if you are allergic to simvastatin or any other ingredient in this medicine.
- Do not take if you have liver disease.
- Do not use if you are pregnant or breastfeeding.
- Tell your doctor about all other medicines you are taking, as some can affect this medicine or increase side effects.
- Avoid heavy alcohol use while taking this medicine.
Show 4 more warnings
- Tell your doctor if you are having surgery, as you may need to stop this medicine temporarily.
- Tell your doctor if you have or have had myasthenia (a muscle weakness condition).
- Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, as this can be serious.
- Avoid drinking grapefruit juice while taking this medicine.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose in severe renal impairment. Possible adverse effects include muscle pain and muscular weakness. Consider potential interactions. Avoid grapefruit. (updated 17.4.2023)