Seroquel Prolong

Seroquel Prolong is a medicine that helps treat serious mental health conditions like depression, mania, and schizophrenia.

Form
depottabletti
Strength
150 mg
Active Ingredient
Quetiapine fumarate
Manufacturer
Cheplapharm Arzneimittel GmbH

How to Use

Dosage

Your doctor will tell you how much to take. The usual daily dose is between 150 mg and 800 mg.

Method

Take one tablet once a day. Swallow it whole with water. Do not crush or chew. Take it without food, at least 1 hour before a meal or at bedtime. Avoid grapefruit juice.

Important

The maximum daily dose is 800 mg.

Possible Side Effects

COMMON
  • Dizziness, headache, dry mouth
  • Drowsiness (feeling sleepy)
  • Withdrawal symptoms (trouble sleeping, feeling sick, headache, diarrhea, vomiting, dizziness, and feeling easily annoyed) if stopping treatment suddenly
  • Weight gain
  • Abnormal muscle movements (like trouble starting movements, shaking, feeling restless, or stiff muscles without pain)
  • Changes in certain fat levels in your blood
  • Fast or pounding heartbeat
  • Constipation, indigestion
  • Weakness, swelling in arms or legs
  • Low blood pressure, especially when standing up (can make you dizzy or faint, leading to falls)
  • High blood sugar
  • Vision problems
  • Abnormal dreams, nightmares
  • Increased appetite
  • Irritability
  • Speech or language problems
  • Suicidal thoughts, worsening depression
  • Shortness of breath
  • Vomiting (mostly in older people)
  • Fever
  • Changes in thyroid hormone levels in blood
  • Decrease in certain white blood cells
  • Increased liver enzyme levels in blood
  • Increased prolactin hormone levels (can cause breast swelling in men/women, unexpected milk production, or missed/irregular periods in women)
RARE
  • Seizures (fits)
  • Allergic reactions (like hives and swelling around the skin and mouth)
  • Unpleasant feeling in legs (restless legs syndrome)
  • Difficulty swallowing
  • Uncontrolled movements, especially of the face or tongue
  • Sexual dysfunction
  • Diabetes
  • Changes in your heart's electrical activity seen on an ECG (QT prolongation)
  • Slower than normal heart rate, which can occur at the start of treatment and may be linked to low blood pressure and fainting
  • Difficulty urinating
  • Fainting (can lead to falls)
  • Stuffy nose
  • Decrease in red blood cells
  • Decrease in sodium levels in blood
  • Worsening of diabetes
  • Confusion
  • A serious condition with high fever, sweating, very stiff muscles, and severe drowsiness or weakness (neuroleptic malignant syndrome)
  • Yellow skin and eyes (jaundice), liver inflammation
  • Long-lasting, painful erection
  • Breast swelling and unexpected milk production
  • Menstrual disorders
  • Blood clots, especially in leg veins (with swelling, pain, redness), which can travel to the lungs causing chest pain and breathing problems
  • Sleepwalking, sleep-talking, sleep-eating, or other activities during sleep
  • Drop in body temperature (hypothermia)
  • Pancreatitis (inflammation of the pancreas)
  • Metabolic syndrome (a combination of symptoms including belly fat, low "good" cholesterol, high triglycerides, high blood pressure, and high blood sugar)
  • Very low white blood cell count (agranulocytosis), possibly with fever, flu-like symptoms, sore throat, or other infection
  • Bowel obstruction
  • Increased levels of an enzyme from muscles (creatine phosphokinase) in blood
  • Severe allergic reaction (anaphylactic shock), which can cause breathing difficulties or shock
  • Rapid swelling of the skin, usually around the eyes, lips, or throat (angioedema)
  • Abnormal secretion of a hormone that controls urine volume
  • Muscle fiber damage and muscle pain (rhabdomyolysis)
  • Stroke
  • Heart muscle disease (cardiomyopathy) or inflammation of the heart muscle (myocarditis)
  • Blood vessel inflammation (vasculitis), often with a red or purple spotted rash

Important Warnings

  • If you get a high fever, very stiff muscles, sweating, or feel very sleepy or confused, tell your doctor right away.
  • If you have uncontrolled movements, especially of your face or tongue.
  • If you feel very dizzy or sleepy, as this can increase the risk of falls, especially in older people.
  • If you have seizures (fits).
  • If you have a long-lasting, painful erection.
Show 5 more warnings
  • If you have a fast or irregular heartbeat, even at rest, palpitations, breathing problems, chest pain, or unexplained tiredness.
  • If you get a fever, flu-like symptoms, sore throat, or any other infection, as this could mean you have very few white blood cells.
  • If you get severe skin reactions such as widespread rash with blisters and peeling skin (Stevens-Johnson syndrome), widespread skin loss, or flu-like symptoms with rash, fever, swollen lymph nodes, and abnormal blood tests (DRESS syndrome).
  • If you have thoughts of harming yourself or suicide.
  • If you have constipation with persistent stomach pain or constipation that doesn't get better, as this could lead to a serious bowel blockage.