Serenase
Serenase is a medicine that helps manage thoughts, feelings, and behaviors in adults and children with certain mental health conditions like schizophrenia and bipolar disorder, and also helps control movement disorders.
How to Use
Dosage
Your doctor will tell you how much Serenase to take. The usual dose for adults is 0.5 to 10 mg daily. For children and adolescents (6-17 years), the usual dose is 0.5 to 3 mg daily.
Method
Take Serenase by mouth using the special syringe provided. You can mix it with a small amount of water, but not with other liquids. Take the mixture right away.
The maximum daily dose for adults is usually 5-20 mg. For elderly patients or adolescents under 17, the maximum is usually 5 mg per day, unless your doctor says otherwise.
Possible Side Effects
- •Feeling restless or agitated
- •Sleep problems (insomnia)
- •Headache
- •Serious mental health problems like believing things that aren't true (delusions) or seeing, feeling, hearing, or smelling things that aren't there (hallucinations)
- •Depression
- •Abnormal muscle tension
- •Dizziness, especially when sitting or standing up
- •Drowsiness
- •Eyes rolling upwards or fast, uncontrolled eye movements
- •Vision problems, such as blurred vision
- •Low blood pressure
- •Nausea, vomiting
- •Constipation
- •Dry mouth or increased saliva
- •Skin rash
- •Difficulty urinating or emptying the bladder completely
- •Difficulty getting or keeping an erection (impotence)
- •Weight gain or loss
- •Changes in liver function blood tests
- •Effects on blood cells: low numbers of all types of blood cells, including a severe decrease in white blood cells and platelets (cells that help blood clot)
- •Feeling confused
- •Loss of sex drive or decreased sex drive
- •Epileptic seizures (convulsions)
- •Muscle and joint stiffness
- •Uncontrolled muscle spasms, twitches, and contractions, including neck spasm causing the head to twist to one side
- •Difficulty walking
- •Shortness of breath
- •Liver inflammation or liver problems causing yellowing of the skin or eyes (jaundice)
- •Increased skin sensitivity to sunlight
- •Itching
- •Heavy sweating
- •Menstrual cycle changes, such as missed periods or long, heavy, painful periods
- •Unexpected milk production
- •Breast pain or discomfort
- •Fever
- •Swelling due to fluid retention in the body
- •High blood prolactin hormone level
- •Narrowing of airways in the lungs, causing breathing difficulties
- •Difficulty or inability to open the mouth
- •Difficulty with sexual intercourse
Important Warnings
- Do not take Serenase if you are allergic to haloperidol or any other ingredient in this medicine.
- Be aware of serious side effects like heart problems, uncontrolled body movements, a severe reaction called neuroleptic malignant syndrome, serious allergic reactions, and blood clots. Seek urgent medical help if you experience these.
- Talk to your doctor if you have heart disease, low blood pressure, low potassium or magnesium, a history of brain bleeding or stroke, epilepsy, kidney, liver, or thyroid problems, high prolactin levels, or blood clots.
- Avoid alcohol while taking Serenase, as it can make you sleepy and less alert.
- If you are pregnant or breastfeeding, discuss with your doctor. Serenase can affect your ability to drive or use machines.
Show 1 more warnings
- Serenase contains methylparahydroxybenzoate, which may cause allergic reactions.
Use in Elderly Patients
Avoid use in older adults. Anticholinergic. Sedative. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 10.11.2025)