Serenase
Serenase is a medicine containing haloperidol, used to treat mental health issues and behavioral disorders that affect thoughts, feelings, and behavior.
How to Use
Dosage
The usual dose for adults is 0.5–10 mg daily. For children (6-17 years), it's typically 0.5–3 mg daily, and for elderly patients, treatment often starts with 0.5 mg daily or half of the lowest adult dose.
Method
Take the tablets orally with a little water.
For adults, the maximum daily dose is 5–20 mg, depending on the condition. For elderly patients, it is usually 5 mg daily, unless a doctor advises a higher dose. For adolescents up to 17 years for certain conditions, it can be up to 5 mg daily.
Possible Side Effects
- •Restlessness
- •Difficulty sleeping
- •Headache
- •Severe mental health issues (delusions, hallucinations)
- •Depression
- •Abnormal muscle tension
- •Dizziness (especially when standing up)
- •Drowsiness
- •Upward eye rolling or uncontrolled eye movements
- •Blurred vision
- •Low blood pressure
- •Nausea
- •Vomiting
- •Constipation
- •Dry mouth or increased saliva
- •Rash
- •Inability to urinate or empty the bladder completely
- •Erectile dysfunction
- •Weight changes
- •Abnormal liver function tests
- •Changes in blood cell count (low white blood cells, platelets)
- •Confusion
- •Decreased libido
- •Epileptic seizures (convulsions)
- •Muscle and joint stiffness
- •Uncontrolled muscle spasms (e.g., neck spasms)
- •Difficulty walking
- •Shortness of breath
- •Liver inflammation or jaundice (yellowing of skin/eyes)
- •Increased sensitivity to sunlight
- •Itching
- •Heavy sweating
- •Menstrual cycle changes (missed, heavy, painful periods)
- •Unexpected milk discharge
- •Breast pain or discomfort
- •Fever
- •Fluid retention (swelling)
- •High prolactin levels
- •Narrowed airways causing breathing difficulties
- •Difficulty opening mouth
- •Difficulty with sexual intercourse
- •High antidiuretic hormone levels (SIADH)
- •Low blood sugar
- •Swelling around larynx or vocal cord spasm (speech/breathing difficulties)
- •Sudden liver failure
- •Reduced bile flow
- •Skin flaking or peeling
- •Capillary inflammation (rash/spots)
- •Muscle tissue breakdown (rhabdomyolysis)
- •Prolonged painful erection
- •Enlarged breasts in men
- •Low body temperature
Important Warnings
- Serenase can cause heart problems, such as irregular heart rhythm, abnormally fast heart rate, or extra heartbeats, which can cause fainting. Seek immediate medical attention if these occur.
- A serious condition called Neuroleptic Malignant Syndrome may occur, causing high fever, severe muscle stiffness, confusion, and loss of consciousness. Seek immediate medical attention if these occur.
- Uncontrolled movements of the mouth, tongue, jaw, or limbs; restlessness; slow or weakened body movements; muscle tremors or stiffness; difficulty walking; or a mask-like face may occur (extrapyramidal symptoms).
- Severe allergic reactions, including swelling of the face, lips, mouth, tongue, or throat; difficulty swallowing or breathing; or itchy rash (hives) may occur. Seek immediate medical attention if these occur.
- Blood clots, especially in the legs (deep vein thrombosis), can cause swelling, pain, and redness. These may travel to the lungs, causing chest pain and difficulty breathing. Seek immediate medical attention if these occur.
Use in Elderly Patients
Avoid use in older adults. Anticholinergic. Sedative. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 10.11.2025)