Sendolor
Sendolor contains morphine, a strong pain reliever, used for severe acute pain, cancer-related pain, and breakthrough cancer pain.
Form
injektioneste, liuos
Strength
10 mg/ml
Active Ingredient
Morphine hydrochloride trihydrate
Manufacturer
Eurocept International BV
How to Use
Dosage
Your doctor will determine your exact dose based on your pain and other factors. Typical doses for adults are 2.5-15 mg intravenously or 5-20 mg (usually 10 mg) subcutaneously or intramuscularly.
Method
Sendolor is given as an injection into a vein, under the skin, or into a muscle. It can also be given as an infusion into the epidural space or intrathecally (into the spinal fluid).
Important
The maximum daily dose is determined by your doctor and depends on the administration method, typically not exceeding 10 mg per day for epidural use, but can be higher for other methods under medical supervision.
Possible Side Effects
COMMON
- •Drowsiness
- •Confusion
- •Insomnia
- •Dizziness
- •Headache
- •Sedation
- •Pupil constriction
- •Loss of appetite
- •Dry mouth
- •Vomiting
- •Constipation
- •Nausea
- •Contact dermatitis
- •Sweating
- •Urinary retention
RARE
- •Allergic reaction
- •Agitation
- •Euphoria (exaggerated feeling of well-being)
- •Hallucinations
- •Mood changes
- •Dysphoria (mental discomfort)
- •Convulsions
- •Muscle rigidity
- •Slow heart rate
- •Fast heart rate
- •Facial flushing
- •Respiratory depression (severe breathing difficulties)
- •Itching
- •Pain and irritation at the injection site
- •Postural hypotension (dizziness or low blood pressure when standing up)
- •Drug dependence
- •Increased pain sensitivity (hyperalgesia)
- •Changes in liver enzyme values
- •Reduced sex drive or impotence
- •Withdrawal symptoms
- •Drug tolerance
- •Sleep apnea (breathing pauses during sleep)
- •Symptoms of pancreatitis or gallbladder issues, such as severe upper abdominal pain radiating to the back, nausea, vomiting, or fever.
Important Warnings
- Do not use if you are allergic to morphine or any other ingredient in this medicine.
- Do not use if you have severe breathing problems (e.g., excessive mucus in airways, severe shortness of breath).
- Do not use if you have acute liver disease.
- This medicine can cause dependence, addiction, and tolerance, meaning you might need more to get the same effect.
- Seek immediate medical help if you experience a severe skin reaction with blisters, widespread peeling, pus-filled spots, and fever.
Show 2 more warnings
- Sendolor can cause sleep-related breathing problems like sleep apnea; contact your doctor if you or someone else notices these symptoms.
- Contact your doctor if you experience severe upper abdominal pain that may spread to your back, with nausea, vomiting, or fever, as these could be signs of pancreatitis.