Salazopyrin
Salazopyrin prevents inflammation and kills bacteria, especially relieving inflammation of the bowel lining.
Form
tabletti
Strength
500 mg
Active Ingredient
Sulfasalazine
Manufacturer
Pfizer Oy
How to Use
Dosage
For rheumatoid arthritis, start with 1 tablet once daily, then typically 2 tablets twice daily; for inflammatory bowel diseases, adults take 2-4 tablets 2-4 times daily, while children's dose depends on weight.
Method
Take tablets with meals, spread evenly throughout the day.
Important
The maximum daily dose is determined by your doctor; for inflammatory bowel diseases, adults may take up to 16 tablets (8000 mg) per day.
Possible Side Effects
COMMON
- •Stomach pain, nausea
- •Low white blood cell count (leukopenia)
- •Loss of appetite
- •Dizziness, headache, taste disturbances
- •Ringing in the ears (tinnitus)
- •Cough
- •Abdominal pain, diarrhea, vomiting
- •Red spots on the skin (purpura), itching
- •Joint pain
- •Protein in urine (proteinuria)
- •Fever
RARE
- •Low platelet count (thrombocytopenia)
- •Depression
- •Shortness of breath
- •Yellowing of skin/eyes (jaundice)
- •Hair loss, hives
- •Facial swelling
- •Increased liver enzyme levels
- •Meningitis, colitis
- •Changes in blood tests (e.g., low blood cells, anemia)
- •Severe allergic reaction, serum sickness
- •Folate deficiency
- •Brain or nerve disease, impaired sense of smell
- •Inflammation of heart muscle or sac around heart, bluish skin
- •Pale skin
- •Lung changes (e.g., inflammation of lung air sacs)
- •Worsening of ulcerative colitis, pancreatitis
- •Liver failure, hepatitis, bile duct blockage
- •Severe skin reactions (e.g., DRESS, Stevens-Johnson syndrome, blistering skin, angioedema, red skin, light sensitivity)
- •Lupus, autoimmune disease (Sjögren's syndrome)
- •Kidney inflammation, kidney stones, blood in urine
- •Temporary low sperm count
- •Yellowing of the skin and body fluids
- •Antibody production
Important Warnings
- This medicine can cause severe allergic reactions, including serious skin rashes or reactions affecting organs, which can be life-threatening. Stop taking it and contact a doctor immediately if you notice skin rashes or other signs of allergy.
- Tell your doctor about any kidney or liver problems, severe allergies, asthma, or if you have glucose-6-phosphate dehydrogenase deficiency, juvenile rheumatoid arthritis, or abnormal blood counts, before taking this medicine. Also, inform your doctor about all other medicines you are taking, as they may affect blood or urine test results.
- Watch out for symptoms like sore throat, fever, pale skin, purple spots on the skin, or yellow skin (jaundice), as these could be signs of serious problems with your bone marrow, red blood cells, or liver. If these occur, stop treatment and get blood tests done.
- Drink plenty of fluids to help prevent kidney stones. This medicine may also harmlessly turn your skin, sweat, saliva, urine, tears, and soft contact lenses yellow or orange.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Consider renal impairment. Do not use in severe renal impairment. Remember blood tests to monitor safety. (updated 10.11.2025)