Saizen
Saizen is a growth hormone that helps children and teenagers grow and treats growth hormone deficiency in adults.
Form
injektioneste, liuos, sylinteriampulli
Strength
8 mg/ml
Active Ingredient
Somatropin
Manufacturer
MERCK OY
How to Use
Dosage
Your doctor will determine your or your child's specific daily dose based on weight or body surface area.
Method
Saizen is given as a daily injection under the skin, usually in the evening before bedtime.
Important
For adults, the final daily dose rarely goes over 1.0 mg; always follow your doctor's exact instructions for the maximum dose.
Possible Side Effects
COMMON
- •Redness, itching, swelling, rash, pain, inflammation, bleeding, or bruising at the injection site.
- •Local loss of fat under the skin.
- •In adults: tingling, burning, pain, and/or numbness in the fingers (especially thumb, index, and sometimes middle/ring fingers).
- •In adults: swelling in the limbs, muscle pain, numbness, tingling, and joint pain. These effects are usually temporary and occur at the start of treatment.
- •Headache.
RARE
- •Increased pressure inside the skull (headache, nausea, vomiting, double vision, other vision problems) in children.
- •In children: tingling, burning, pain, and/or numbness in the fingers (especially thumb, index, and sometimes middle/ring fingers).
- •In children: swelling in the limbs, muscle pain, numbness, tingling, and joint pain. These effects are usually temporary and occur at the start of treatment.
- •Enlarged breasts (in one or both sides).
- •Hip problems (e.g., slipped thigh bone growth plate, tissue death due to poor blood supply).
- •Lowered thyroid hormone levels. Your doctor can check this and prescribe treatment if needed.
- •Pancreatitis (inflammation of the pancreas).
- •Allergic reactions.
Important Warnings
- Do not use Saizen if you or your child are allergic to somatropin or any other ingredients in this medicine.
- Do not use if your child's bones have stopped growing and they have reached their full adult height.
- Do not use if you have active cancer. Cancer treatment must be completed before starting Saizen.
- Do not use if you or your child have a severe illness (e.g., complications from open heart surgery, severe injury, or acute breathing problems).
- Contact your doctor immediately if you or your child get severe headaches, nausea, vomiting, or vision changes, as these can be signs of a rare but serious side effect called brain swelling.
Show 3 more warnings
- Do not use if you or your child have diabetes with related eye problems (diabetic retinopathy). Your doctor will closely monitor blood sugar and may adjust diabetes treatment.
- Always change the injection site to avoid damage to the skin. Your doctor or pharmacist can show you suitable areas.
- In rare cases, Saizen can cause pancreatitis, which is severe stomach and back pain. Contact your doctor if you or your child experience such pain.