Sacubitril/Valsartan Krka
Sacubitril/Valsartan Krka is a heart medicine used to treat a specific type of chronic heart failure in adults and children aged 1 year and older.
Form
tabletti, kalvopäällysteinen
Strength
49 mg / 51 mg
Active Ingredient
Sacubitril sodium
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The usual starting dose is one 24 mg/26 mg or 49 mg/51 mg tablet twice a day (one in the morning and one in the evening). Your doctor may adjust the dose every 2-4 weeks. The usual target dose is 97 mg/103 mg twice a day.
Method
Swallow the tablet whole with a glass of water. You can take it with or without food. Do not break or crush the tablets.
Important
The maximum recommended daily dose is 194 mg/206 mg, achieved by taking 97 mg/103 mg twice daily.
Possible Side Effects
COMMON
- •low blood pressure (which can cause dizziness and light-headedness)
- •high potassium levels in the blood (seen in blood tests)
- •worsening kidney function
- •cough
- •light-headedness
- •diarrhoea
- •low red blood cell count (seen in blood tests)
- •tiredness
- •sudden inability of the kidneys to work properly (acute renal failure)
- •low potassium levels in the blood (seen in blood tests)
- •headache
- •fainting
- •weakness
- •nausea
- •low blood pressure (dizziness, fainting) when changing position from sitting or lying to standing
- •stomach inflammation (stomach pain, nausea)
- •spinning sensation (dizziness)
- •low blood sugar levels (seen in blood tests)
RARE
- •allergic reaction with rash and itching
- •dizziness when standing up from sitting or lying down (postural dizziness)
- •low sodium levels in the blood (seen in blood tests)
- •seeing, hearing or feeling things that are not there (hallucinations)
- •changes in sleep patterns (sleep disorders)
- •paranoia
- •intestinal angioedema: swelling in the intestines with symptoms like stomach pain, nausea, vomiting, and diarrhoea
- •sudden involuntary muscle twitching
Important Warnings
- If you experience swelling of your face, lips, tongue, or throat, stop taking the medicine and seek immediate medical help. This could be a serious allergic reaction called angioedema.
- Do not take this medicine if you are currently taking blood pressure medicines called ACE inhibitors. Wait 36 hours after your last ACE inhibitor dose before starting Sacubitril/Valsartan Krka.
- Do not use this medicine if you are pregnant (especially if more than 3 months pregnant) or breastfeeding.
- Do not take this medicine if you have severe liver disease.
- Do not take this medicine if you have diabetes or poor kidney function and are also taking a blood pressure medicine that contains aliskiren.
Show 1 more warnings
- Do not give this medicine to children under 1 year of age.