Sacubitril/Valsartan Devatis
This medicine helps treat a type of long-term heart failure in adults and children aged one year and older.
Form
tabletti, kalvopäällysteinen
Strength
49 mg / 51 mg
Active Ingredient
Sacubitril sodium
Manufacturer
Devatis GmbH
How to Use
Dosage
Usually, take one tablet (24 mg/26 mg or 49 mg/51 mg) twice a day, one in the morning and one in the evening. Your doctor will adjust your dose to find what works best for you.
Method
Swallow the tablet whole with water. You can take it with or without food. Do not split or crush the tablets.
Important
The maximum recommended daily dose for adults is one 97 mg/103 mg tablet twice a day.
Possible Side Effects
COMMON
- •Low blood pressure, which can cause dizziness or lightheadedness.
- •High potassium levels in the blood (seen in blood tests).
- •Reduced kidney function.
- •Cough.
- •Dizziness.
- •Diarrhea.
- •Reduced red blood cell count (seen in blood tests).
- •Tiredness.
- •Headache.
- •Fainting.
- •Weakness.
- •Nausea.
- •Dizziness when standing up from a sitting or lying position.
- •Stomach inflammation (stomach pain, nausea).
- •Low blood sugar (seen in blood tests).
RARE
- •Allergic reaction with rash and itching.
- •Low sodium levels in the blood (seen in blood tests).
- •Hallucinations (seeing, hearing, or feeling things that are not there).
- •Sleep disturbances.
- •Paranoia.
- •Swelling in the intestines (intestinal angioedema), with symptoms like stomach pain, nausea, vomiting, and diarrhea.
- •Sudden, involuntary muscle twitching.
Important Warnings
- Do not take if you are allergic to sacubitril, valsartan, or any other ingredients in this medicine.
- Do not take this medicine if you are also taking ACE inhibitors. Wait 36 hours after your last ACE inhibitor dose before starting this medicine.
- Do not take if you have ever had a severe allergic reaction (angioedema) causing swelling of the face, lips, tongue, or throat.
- Do not use this medicine if you are more than 3 months pregnant or if you are breastfeeding. Talk to your doctor if you are planning to become pregnant or are breastfeeding.
- Do not take if you have severe liver disease.
Show 2 more warnings
- Do not take if you have diabetes or impaired kidney function and are taking a blood pressure-lowering medicine containing aliskiren.
- If you feel dizzy or very tired, do not drive or operate machinery.