Ropinostad
Ropinostad is a medication containing ropinirole, used to treat Parkinson's disease by mimicking natural dopamine in the brain.
How to Use
Dosage
The starting dose is usually 2 mg once daily for the first week, which may be increased to 4 mg once daily from the second week; your doctor will adjust the dose to find what works best for you.
Method
Take Ropinostad once a day at the same time, swallowed whole with a glass of water. Do not break, chew, or crush the tablets. You can take it with or without food.
Some patients may take up to 24 mg of Ropinostad prolonged-release tablets per day.
Possible Side Effects
- •Fainting
- •Feeling sleepy
- •Nausea
- •Suddenly falling asleep without feeling tired
- •Hallucinations (seeing, hearing, or feeling things that aren't there)
- •Vomiting
- •Dizziness (a spinning sensation)
- •Heartburn
- •Stomach pain
- •Constipation
- •Swelling of the legs, feet, or hands
- •Uncontrolled movements (dyskinesias)
- •Confusion
- •Dizziness or light-headedness, especially when standing up suddenly (due to a drop in blood pressure)
- •Low blood pressure
- •Extreme daytime sleepiness
- •Mental problems such as severe confusion (delirium), false beliefs (delusions), or strong suspicion (paranoia)
- •Hiccups
- •Allergic reactions like red, itchy skin lumps, swelling of the face, lips, mouth, tongue, or throat causing difficulty swallowing or breathing, rash, or severe itching
- •Changes in liver function (seen in blood tests)
- •Aggressiveness
- •Craving for higher doses of Ropinostad than needed for motor symptoms (Dopamine Dysregulation Syndrome)
- •Inability to resist impulses or urges that could harm yourself or others, such as severe gambling addiction, excessive spending, unusually strong sex drive or sexual thoughts, or compulsive overeating
- •Periods of overactivity, elevated mood, or irritability (mania symptoms)
- •After stopping or reducing Ropinostad: depression, apathy, anxiety, tiredness, sweating, or pain (Dopamine Agonist Withdrawal Syndrome)
- •Spontaneous erection
Important Warnings
- Do not take if you are allergic to ropinirole or any other ingredient in this medicine.
- Do not take if you have severe kidney or liver disease.
- Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine is generally not recommended during pregnancy or breastfeeding.
- Not recommended for people under 18 years of age.
- Tell your doctor if you have severe heart problems or serious mental health issues.
Show 4 more warnings
- Inform your doctor if you experience unusual urges or behaviors like gambling, excessive spending, increased sex drive, overeating, or sudden mood changes (mania).
- This medicine can cause extreme sleepiness or make you fall asleep suddenly. Do not drive or use machines if you experience this.
- Do not stop taking this medicine suddenly without your doctor's advice, as it can worsen Parkinson's symptoms or cause a serious reaction.
- Ropinostad 4 mg tablets contain the dye 'para-orange (E110)', which may cause allergic reactions.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Sedative. Common adverse effects include orthostatic hypotension, confusion, sudden episodes of deep sleep, impulse control disorders and lower limb edema.. . (updated 6.10.2025)