Risperidon ratiopharm
Risperidon ratiopharm is a medicine used to treat schizophrenia, helping to reduce symptoms like hallucinations and confusion, and prevent them from returning.
Form
injektiokuiva-aine ja liuotin, depotsuspensiota varten
Strength
25 mg
Active Ingredient
Risperidone
Manufacturer
ratiopharm GmbH
How to Use
Dosage
Your doctor will decide your dose, typically 25 mg given every two weeks, but higher doses (37.5 mg or 50 mg) may be needed.
Method
A healthcare professional will give you this medicine as an injection into a muscle (either your arm or buttock) every two weeks. Injection sites should be rotated, and it should not be given into a vein.
Important
The highest single dose per injection is 50 mg, as determined by your doctor.
Possible Side Effects
COMMON
- •Flu-like symptoms
- •Difficulty sleeping
- •Depression, anxiety
- •Parkinsonism (slow movement, stiff muscles, tremors)
- •Headache
- •Chest infections, urinary tract infections, flu-like feeling
- •Anemia
- •Increased levels of prolactin hormone
- •High blood sugar, changes in weight or appetite
- •Sleep problems, irritability, reduced sexual desire, restlessness, drowsiness, or difficulty concentrating
- •Dystonia (slow or prolonged involuntary muscle contractions)
- •Dizziness
- •Dyskinesia (involuntary muscle movements)
- •Tremor (shaking)
- •Blurred vision
- •Fast heartbeat
- •Low or high blood pressure, chest pain
- •Shortness of breath, sore throat, cough, blocked nose
- •Stomach pain, nausea, vomiting, diarrhea, constipation, indigestion, dry mouth, toothache
- •Rash
- •Muscle spasms, bone or muscle pain, back pain, joint pain
- •Urinary incontinence
- •Erectile dysfunction
- •Missed menstrual periods
- •Breast milk leakage
- •Swelling of body or limbs, fever, weakness, fatigue
- •Pain
- •Injection site reactions (itching, pain, swelling)
- •Increased liver enzyme levels in blood
- •Falls
RARE
- •Various infections including respiratory, bladder, ear, eye, skin infections, and abscesses
- •Decreased white blood cells, platelets, or red blood cells
- •Allergic reaction
- •Sugar in urine, new or worsening diabetes
- •Loss of appetite and underweight
- •Increased blood fat (triglyceride or cholesterol) levels
- •Elevated mood, confusion, inability to achieve orgasm, nervousness, nightmares
- •Loss of consciousness, seizures, fainting
- •Restlessness, balance problems, dizziness when standing up, difficulty speaking, changes in taste or sensation, tingling or numbness
- •Eye inflammation, dry eyes, increased tears, red eyes
- •Vertigo, ringing in ears, ear pain
- •Heart rhythm problems (e.g., atrial fibrillation, slow heart rate, palpitations)
- •Low blood pressure when standing up (may cause dizziness or fainting)
- •Rapid shallow breathing, swollen airways, wheezing, nosebleeds
- •Fecal incontinence, difficulty swallowing, gas
- •Skin itching, hair loss, eczema, dry or red skin, acne, flaky skin or scalp
- •Increased creatine kinase levels in blood (a muscle enzyme)
- •Stiff joints, joint swelling, muscle weakness, neck pain
- •Frequent or painful urination, inability to empty bladder
- •Sexual problems (ejaculation disorder, changes in menstrual cycle, breast changes, vaginal discharge)
- •Swelling of face, mouth, eyes, or lips
- •Chills, fever
- •Changes in walking style
- •Thirst, malaise, breast discomfort, feeling unwell
- •Skin hardening
- •Abnormal secretion of hormone regulating urine volume
- •Low blood sugar
- •Excessive water intake
- •Sleepwalking
- •Sleep-related eating disorder
- •Catatonia (immobility and unresponsiveness while awake)
- •Lack of emotion
- •Decreased level of consciousness
- •Head shaking
- •Abnormal eye movements, eye rolling, sensitivity to light
- •Eye problems during cataract surgery (e.g., floppy iris syndrome)
- •Irregular heartbeat
- •Dangerously low white blood cells, high eosinophils
- •Sleep apnea (breathing problems during sleep)
- •Pneumonia from inhaling food, lung congestion, voice disorders, breathing difficulties
- •Pancreatitis, intestinal blockage
- •Very hard stools
- •Drug rash
- •Hives, skin thickening, scaling, skin disorders or lesions
- •Rhabdomyolysis (muscle fiber breakdown and pain)
- •Abnormal postures
- •Breast enlargement or discharge
- •Low body temperature, discomfort
- •Jaundice (yellow skin and eyes)
- •Increased insulin levels in blood
- •Cerebrovascular problems
- •Unresponsiveness to stimuli
- •Coma from uncontrolled diabetes
- •Sudden vision loss or blindness
- •Glaucoma (increased eye pressure), crusting of eyelids
- •Swollen, red tongue
- •Chapped lips
- •Decreased body temperature, cold hands and feet
- •Withdrawal symptoms when stopping the medicine
- •Life-threatening complications of uncontrolled diabetes
- •Severe allergic reactions with throat swelling and breathing difficulties
- •Decreased bowel movements, leading to blockage
- •Severe or life-threatening skin rash with blisters and peeling skin (Stevens-Johnson syndrome or toxic epidermal necrolysis)
- •Rapid heartbeat when standing up
Important Warnings
- Do not take this medicine if you are allergic to risperidone or any other ingredients.
- If you have never taken risperidone before, you should start with oral risperidone before getting injections.
- Tell your doctor if you have heart problems, as this medicine can lower blood pressure and your dose might need to be adjusted.
- Tell your doctor if you have risk factors for stroke, such as high blood pressure or blood vessel problems in your brain.
- Tell your doctor if you have ever had involuntary movements of your tongue, mouth, or face.
Show 19 more warnings
- Tell your doctor if you have ever had a condition with symptoms like fever, muscle stiffness, sweating, or reduced consciousness (called Neuroleptic Malignant Syndrome).
- Tell your doctor if you have Parkinson's disease or dementia.
- Tell your doctor if you have had low white blood cell counts in the past.
- Tell your doctor if you have diabetes.
- Tell your doctor if you have epilepsy.
- If you are a man, tell your doctor if you have ever had a prolonged or painful erection.
- Tell your doctor if you have problems regulating your body temperature or if you get high body temperature.
- Tell your doctor if you have kidney disease.
- Tell your doctor if you have liver disease.
- Tell your doctor if you have unusually high levels of a hormone called prolactin, or a tumor that depends on prolactin.
- Tell your doctor if you or a family member has a history of blood clots, as this medicine can increase the risk of clots.
- Your doctor may check your white blood cell count because a very low level of a certain type of white blood cells has been rarely seen with this medicine.
- Seek immediate medical attention if you experience signs of a serious allergic reaction like rash, swelling of the throat, itching, or difficulty breathing, even if you previously tolerated oral risperidone.
- This medicine can cause weight gain; your doctor will regularly check your weight.
- Your doctor will check for signs of high blood sugar or new/worsening diabetes.
- This medicine can increase prolactin levels, which may cause menstrual problems or infertility in women, and breast swelling in men.
- If you are having eye surgery, tell your eye doctor that you are taking this medicine, as it can affect your pupils during cataract surgery.
- This medicine is not for elderly patients with dementia.
- Seek medical help immediately if you notice sudden changes in mental state, weakness or numbness on one side of the face, arms, or legs, or slurred speech, as these could be signs of a stroke.
Use in Elderly Patients
Category D
Avoid use in older adults. For treatment of psychosis only. Use only in special cases and for a limited time in the management of severe behavioural symptoms of cognitive impairment. Reduce the dose already in mild renal impairment. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk for falls and extrapyramidal symptoms. (updated 15.1.2024)