Quetiapine Accord
Quetiapine Accord is a medicine used to treat mental health conditions like schizophrenia, mania, and depression.
Form
depottabletti
Strength
400 mg
Active Ingredient
Quetiapine fumarate
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor will tell you how much to take. The usual daily dose is between 150 mg and 800 mg.
Method
Take the tablets once a day, whole with water. Take them at least one hour before a meal or at bedtime, as advised by your doctor. Do not split, chew, or crush them. Do not drink grapefruit juice.
Important
The maximum daily dose is usually 800 mg.
Possible Side Effects
COMMON
- •Dizziness (can lead to falls)
- •Headache
- •Dry mouth
- •Feeling sleepy (this may go away with continued use of the tablets) (can lead to falls)
- •Withdrawal symptoms (symptoms that occur when you stop taking Quetiapine Accord) including difficulty sleeping, feeling sick, headache, diarrhea, vomiting, dizziness, and irritability. It is advisable to stop the medicine gradually over 1-2 weeks.
- •Weight gain
- •Abnormal muscle movements, such as difficulty starting movements, shaking, restlessness or muscle stiffness without pain.
- •Changes in certain fat levels (triglycerides and total cholesterol)
RARE
- •Fast heart rate
- •Palpitations, feeling like your heart is pounding or skipping a beat
- •Constipation, upset stomach (indigestion)
- •Weakness
- •Swelling in arms or legs
- •Low blood pressure when standing up (can make you feel dizzy or faint, leading to falls)
- •High blood sugar
- •Blurred vision
- •Abnormal dreams and nightmares
- •Increased hunger
- •Irritability
- •Speech and language problems
- •Thoughts of suicide and worsening depression
- •Shortness of breath
- •Vomiting (mainly in older people)
- •Fever
- •Changes in thyroid hormone levels in the blood
- •Decrease in certain types of white blood cells
- •Increase in liver enzymes measured in blood tests
- •Increase in prolactin hormone in the blood (rarely leading to breast swelling and unexpected milk production in men and women, or missed/irregular periods in women)
- •Seizures
- •Allergic reactions (e.g., hives, swelling of skin and around mouth)
- •Unpleasant feeling in legs (restless legs syndrome)
- •Difficulty swallowing
- •Uncontrolled movements, especially in the face or tongue
- •Sexual dysfunction
- •Changes in heart's electrical activity seen on ECG (QT prolongation)
- •Diabetes
- •Slower than normal heart rate (may occur at the start of treatment or with low blood pressure and fainting)
- •Difficulty urinating
- •Fainting (can lead to falls)
- •Stuffy nose
- •Decrease in red blood cells
- •Decrease in sodium in the blood
- •Worsening of diabetes
- •Confusion
- •A combination of fever, sweating, muscle stiffness, strong drowsiness or fainting (Neuroleptic Malignant Syndrome)
- •Yellow skin and eyes (jaundice)
- •Liver inflammation (hepatitis)
- •Prolonged and painful erection (priapism)
- •Breast swelling and unexpected milk production (galactorrhea)
- •Menstrual disorders
- •Blood clots in veins, especially in the legs (symptoms like swelling, pain, and redness in the legs), which can travel to the lungs causing chest pain and breathing difficulties. Seek medical help immediately if you have these symptoms.
- •Walking, talking, or eating in your sleep
- •Decreased body temperature (hypothermia)
- •Inflammation of the pancreas (pancreatitis)
- •Metabolic syndrome (a condition with at least three of the following: increased fat around the abdomen, decreased "good cholesterol" (HDL-C), increased blood fats called triglycerides, high blood pressure, and increased blood sugar)
- •A combination of fever, flu-like symptoms, sore throat or other infection with a very low number of white blood cells (agranulocytosis)
- •Bowel blockage
- •Increased levels of creatine phosphokinase in the blood (a substance from muscles)
- •Severe rash, blisters or red patches on the skin
- •Severe allergic reaction (e.g., difficulty breathing, dizziness or shock)
- •Sudden swelling of the skin, usually around the eyes, lips or throat (angioedema)
- •Severe blistering on the skin, mouth, eyes, or genitals (Stevens-Johnson syndrome)
- •Abnormal secretion of a hormone that regulates urine volume
- •Muscle breakdown and muscle pain (rhabdomyolysis)
- •Rash with irregular red patches (erythema multiforme)
- •Rapidly appearing red skin areas full of small pus-filled blisters (acute generalized exanthematous pustulosis (AGEP))
- •Severe, sudden allergic reaction with symptoms like fever, skin blisters, and skin peeling (toxic epidermal necrolysis)
- •Drug reaction with eosinophilia and systemic symptoms (DRESS), with flu-like symptoms, rash, fever, swollen lymph nodes, and unusual blood values
- •Withdrawal symptoms in newborns if mother used Quetiapine Accord during pregnancy
- •Stroke
- •Heart muscle disease (cardiomyopathy)
- •Inflammation of the heart muscle (myocarditis)
- •Inflammation of blood vessels (vasculitis), often with rash with small red or purple lumps
Important Warnings
- Do not take if you are allergic to quetiapine or any other ingredients.
- Do not take if you are using certain HIV medicines, medicines for fungal infections, erythromycin, clarithromycin, or nefazodone.
- Seek immediate medical help if you experience a high fever, severe muscle stiffness, sweating, or a reduced level of consciousness.
- Tell your doctor right away if you have uncontrolled movements, especially in your face or tongue.
- This medicine can cause dizziness or severe drowsiness, which may lead to falls, especially in older people.
Show 12 more warnings
- Contact your doctor if you have seizures or a painful erection that lasts a long time.
- Tell your doctor as soon as possible if you get a fever, flu-like symptoms, sore throat, or any infection, as this could mean you have a very low number of white blood cells.
- If you have severe constipation or stomach pain that does not go away, tell your doctor immediately as it could lead to a serious bowel blockage.
- If you are depressed, you might have thoughts of harming yourself or suicide. Contact your doctor or nearest hospital immediately if you have such thoughts.
- Stop taking this medicine and seek urgent medical attention if you get severe skin reactions like widespread rash with blisters and peeling skin, flu-like symptoms with rash, fever, and swollen glands, or rash with red patches.
- Weight gain has been seen in patients using Quetiapine Accord. You and your doctor should check your weight regularly.
- Quetiapine Accord should not be used by children or adolescents under 18 years of age.
- Do not drink grapefruit juice while taking this medicine as it can affect how the medicine works.
- Be careful with alcohol as it can make you very sleepy when combined with Quetiapine Accord.
- Do not take this medicine if you are pregnant or breastfeeding unless you have discussed it with your doctor.
- This medicine can make you sleepy. Do not drive or use machines until you know how it affects you.
- Do not stop taking your tablets suddenly, even if you feel better, without first talking to your doctor.