Quetiapine Accord

Quetiapine Accord is a medicine used to treat mental health conditions such as schizophrenia, mania, and depression in bipolar disorder.

Form
depottabletti
Strength
200 mg
Active Ingredient
Quetiapine fumarate
Manufacturer
Accord Healthcare B.V.

How to Use

Dosage

Your doctor will decide your dose, typically between 150 mg and 800 mg per day.

Method

Take the tablets once a day, whole with water, without food (at least 1 hour before a meal or at bedtime). Do not break, chew, or crush them. Avoid grapefruit juice.

Important

The maximum daily dose is 800 mg.

Possible Side Effects

COMMON
  • Dizziness, headache, dry mouth
  • Feeling sleepy, which might cause falls
  • Symptoms like trouble sleeping, nausea, headache, diarrhea, vomiting, dizziness, and irritability if you stop the medicine suddenly
  • Weight gain
  • Abnormal muscle movements, like shaking, stiffness, or being restless
  • Changes in fat levels (triglycerides and cholesterol) in your blood
  • Fast heartbeat
  • Pounding or racing heart
  • Constipation, upset stomach
  • Feeling weak
  • Swelling in your arms or legs
  • Low blood pressure when standing up, making you feel dizzy or faint
  • High blood sugar
  • Blurred vision
  • Strange dreams or nightmares
  • Increased appetite
  • Irritability
  • Problems with speech or talking
  • Thoughts of harming yourself or worsening depression
  • Shortness of breath
  • Vomiting (more common in older people)
  • Fever
  • Changes in thyroid hormone levels in your blood
  • Lower numbers of certain white blood cells
  • Higher liver enzyme levels in your blood
  • Increased levels of a hormone called prolactin in your blood, which can sometimes cause breast swelling or irregular periods
RARE
  • Seizures
  • Allergic reactions, such as skin rash or swelling around the mouth
  • Unpleasant feeling in the legs (restless legs syndrome)
  • Difficulty swallowing
  • Uncontrolled movements, especially of the face or tongue
  • Sexual problems
  • Changes in your heart's electrical activity (seen on an ECG)
  • Diabetes
  • Slower heart rate than usual, especially when starting treatment or with low blood pressure and fainting
  • Difficulty urinating
  • Fainting, which might cause falls
  • Blocked nose
  • Lower numbers of red blood cells
  • Lower sodium levels in your blood
  • Worsening diabetes
  • Confusion
  • A serious condition with high fever, sweating, stiff muscles, and very deep sleep or weakness (neuroleptic malignant syndrome)
  • Yellowing of skin and eyes (jaundice)
  • Liver inflammation
  • Long-lasting and painful erection
  • Breast swelling and unexpected milk production
  • Problems with periods
  • Blood clots, especially in the legs, which can cause chest pain and breathing problems if they travel to the lungs
  • Walking, talking, eating, or other activities in your sleep
  • Low body temperature
  • Inflammation of the pancreas (pancreatitis)
  • Metabolic syndrome, which includes a combination of increased fat around your waist, low "good" cholesterol, high blood fats, high blood pressure, and high blood sugar
  • A very low number of white blood cells (agranulocytosis) with fever, flu-like symptoms, or sore throat
  • Blockage in your bowel
  • Increased levels of a muscle substance (creatine phosphokinase) in your blood
  • Severe skin rash, blisters, or red patches
  • Severe allergic reaction (anaphylactic shock) that can cause trouble breathing or shock
  • Sudden swelling of the skin, often around the eyes, lips, or throat (angioedema)
  • Serious blistering on the skin, in your mouth, eyes, or private parts (Stevens-Johnson syndrome)
  • Abnormal release of a hormone that controls how much you urinate
  • Muscle breakdown and muscle pain (rhabdomyolysis)

Important Warnings

  • Do not take this medicine if you are allergic to quetiapine or any of its ingredients.
  • Do not take this medicine if you are taking certain HIV medications, antifungal medicines, erythromycin or clarithromycin (for infections), or nefazodone (for depression).
  • Seek immediate medical help if you experience a combination of fever, severe muscle stiffness, sweating, or decreased consciousness (called neuroleptic malignant syndrome).
  • Tell your doctor immediately if you have uncontrolled movements, especially of your face or tongue.
  • Tell your doctor immediately if you feel dizzy or very sleepy, as this can increase the risk of falls, especially in older people.
Show 2 more warnings
  • Tell your doctor immediately if you experience seizures.
  • Tell your doctor immediately if you have a prolonged and painful erection (priapism).