Quetiapin Orion
Quetiapin Orion is a medicine that helps treat serious mental health conditions like bipolar disorder, mania, and schizophrenia.
Form
tabletti, kalvopäällysteinen
Strength
25 mg
Active Ingredient
Quetiapine fumarate
Manufacturer
Orion Corporation
How to Use
Dosage
Your doctor will tell you how much to take. The usual daily dose is between 150 mg and 800 mg.
Method
Take your tablets once a day at bedtime or twice a day, as directed by your doctor. Swallow them whole with water, with or without food. Do not drink grapefruit juice.
Important
Do not take more than 800 mg in one day, unless your doctor tells you to.
Possible Side Effects
COMMON
- •Dizziness (can lead to falls)
- •Headache
- •Dry mouth
- •Drowsiness (may disappear with continued treatment, can lead to falls)
- •Withdrawal symptoms (insomnia, nausea, headache, diarrhea, vomiting, dizziness, irritability) if stopped suddenly.
- •Weight gain
- •Abnormal muscle movements (difficulty starting movements, tremors, restlessness, muscle stiffness without pain)
- •Changes in certain fat levels in the blood (triglycerides and total cholesterol)
- •Fast heartbeat
- •Palpitations (pounding or fluttering heart)
- •Constipation, indigestion
- •Weakness
- •Swelling of hands or feet
- •Low blood pressure, especially when standing up (can cause dizziness or faintness, leading to falls)
- •High blood sugar
- •Blurred vision
- •Abnormal dreams and nightmares
- •Increased appetite
- •Irritability
- •Speech and language problems
- •Suicidal thoughts and worsening depression
- •Shortness of breath
- •Vomiting (mainly in the elderly)
- •Fever
- •Changes in blood thyroid hormone levels
- •Decrease in certain types of white blood cells
- •Increase in liver enzymes (measured in blood tests)
- •Increased prolactin levels in blood, which can rarely cause breast swelling and unexpected milk production in men and women, or missed/irregular periods in women.
RARE
- •Seizures or fits
- •Allergic reactions, such as hives or swelling of the skin and around the mouth
- •Uncomfortable feeling in the legs (restless legs syndrome)
- •Difficulty swallowing
- •Uncontrolled movements, especially of the face or tongue
- •Sexual problems
- •Diabetes (or worsening diabetes)
- •Changes in the heart's electrical activity seen on an ECG (QT prolongation)
- •Slower heart rate than normal, especially at the start of treatment, possibly with low blood pressure and fainting
- •Difficulty urinating
- •Fainting (can lead to falls)
- •Nasal congestion
- •Decrease in red blood cells
- •Decrease in blood sodium
- •Confusion
- •Combination of fever, sweating, muscle stiffness, severe drowsiness or weakness (neuroleptic malignant syndrome)
- •Yellow skin and eyes (jaundice)
- •Liver inflammation (hepatitis)
- •Long-lasting and painful erection (priapism)
- •Breast swelling and unexpected milk production (galactorrhea)
- •Menstrual disorders
- •Blood clots in veins, especially in the legs (swelling, pain, redness) which can travel to the lungs, causing chest pain and breathing difficulties. Seek medical help immediately if this happens.
- •Sleepwalking, sleep-talking, sleep-eating or other activities while asleep
- •Drop in body temperature (hypothermia)
- •Inflammation of the pancreas (pancreatitis)
- •Metabolic syndrome (a combination of central obesity, low 'good' cholesterol, high triglycerides, high blood pressure, and high blood sugar)
- •Fever, flu-like symptoms, sore throat or other infection with very low white blood cell count (agranulocytosis)
- •Bowel obstruction
- •Increased levels of creatinine phosphokinase (a substance from muscles) in the blood
- •Severe rash, blisters or red patches on the skin
- •Severe allergic reaction (anaphylactic shock) that may cause breathing difficulties or shock
- •Sudden swelling of the skin, usually around the eyes, lips and throat (angioedema)
- •Severe blistering disease of the skin, mouth, eyes and genitals (Stevens-Johnson syndrome)
- •Disrupted secretion of a hormone that regulates urine volume
- •Breakdown of muscle fibers and muscle pain (rhabdomyolysis)
- •Rash with irregular red spots (erythema multiforme)
- •Rapidly appearing red skin areas full of small pus-filled blisters (acute generalized exanthematous pustulosis, AGEP)
- •Severe, sudden allergic reaction with symptoms like fever, skin blisters and peeling (toxic epidermal necrolysis)
- •Drug rash with eosinophilia and systemic symptoms (DRESS) which consists of flu-like symptoms, rash, fever, swollen glands and abnormal blood test results
- •Heart muscle disease (cardiomyopathy)
- •Heart muscle inflammation (myocarditis)
- •Inflammation of blood vessels (vasculitis), often with rash resembling small red or purple bumps
- •Withdrawal symptoms in newborns if the mother used Quetiapin Orion during pregnancy
- •Stroke
Important Warnings
- Do not take this medicine if you are allergic to quetiapine or any other ingredients listed in the leaflet.
- Contact your doctor immediately if you experience a high fever, severe muscle stiffness, sweating, or confusion (this could be a serious condition called neuroleptic malignant syndrome).
- Tell your doctor right away if you have uncontrolled movements, especially of your face or tongue.
- Seek immediate medical attention if you develop severe skin reactions like widespread rash with blisters, peeling skin, or flu-like symptoms (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS, AGEP, or erythema multiforme).
- If you feel dizzy or very sleepy, it could increase your risk of falling, especially if you are elderly. Be careful.
Show 3 more warnings
- Do not stop taking this medicine suddenly, even if you feel better, without talking to your doctor first, as withdrawal symptoms may occur.
- This medicine is not for children or adolescents under 18 years of age.
- Be aware that this medicine can sometimes cause suicidal thoughts or worsen depression, especially in young adults.