Quetiapin Krka
Quetiapine Krka is an antipsychotic medicine used to treat conditions like bipolar disorder, mania, and schizophrenia.
Form
depottabletti
Strength
400 mg
Active Ingredient
Quetiapine hemifumarate
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
Your doctor will prescribe the right dose for you; it is usually between 150 mg and 800 mg daily.
Method
Take one tablet once a day whole with water; do not chew or crush it. Take the tablet at least one hour before a meal or at bedtime, and do not drink grapefruit juice.
Important
The maximum daily dose is usually 800 mg, but your doctor will prescribe the correct dose for you.
Possible Side Effects
COMMON
- •Dizziness (may lead to falls)
- •Headache
- •Dry mouth
- •Feeling sleepy (may go away, can lead to falls)
- •Withdrawal symptoms (like trouble sleeping, feeling sick, headache, diarrhea, vomiting, dizziness, feeling annoyed)
- •Weight gain
- •Unusual muscle movements (like trouble starting to move, shaking, feeling restless, or stiff muscles without pain)
- •Changes in blood fats (like triglycerides and total cholesterol)
- •Fast heartbeat
- •Pounding or fluttering heart
- •Constipation
- •Upset stomach
- •Feeling weak
- •Swelling in hands or feet
- •Low blood pressure when standing up (can make you dizzy or faint, can lead to falls)
- •High blood sugar
- •Blurred vision
- •Strange dreams or nightmares
- •More hungry than usual
- •Feeling annoyed
- •Problems with speaking
- •Thoughts of suicide or worse depression
- •Shortness of breath
- •Throwing up (mostly in older people)
- •Fever
- •Changes in thyroid hormone levels in the blood
- •Fewer certain types of white blood cells
- •Higher liver enzymes in blood tests
- •Higher levels of prolactin hormone in the blood (can rarely cause breast swelling in men and women, unexpected milk, or missed/irregular periods in women)
RARE
- •Seizures
- •Allergic reactions (e.g., hives, swelling of skin and around the mouth)
- •Restless legs syndrome (unpleasant feeling in legs)
- •Difficulty swallowing
- •Uncontrolled movements (especially of the face or tongue)
- •Sexual problems
- •Diabetes
- •Changes in heart's electrical activity (seen on ECG)
- •Slower than normal heart rate (can happen at first, with low blood pressure and fainting)
- •Trouble urinating
- •Fainting (can lead to falls)
- •Stuffy nose
- •Fewer red blood cells
- •Low sodium in blood
- •Worsening diabetes
- •Confusion
- •High fever, sweating, stiff muscles, extreme sleepiness or weakness (Neuroleptic Malignant Syndrome)
- •Yellow skin and eyes (jaundice)
- •Liver inflammation (hepatitis)
- •Long-lasting, painful erection (priapism)
- •Breast swelling and unexpected milk (galactorrhea)
- •Irregular periods
- •Blood clots (especially in leg veins, causing swelling, pain, redness; can travel to lungs causing chest pain and breathing problems - get help right away)
- •Sleepwalking, sleep-talking, sleep-eating, or other activities during sleep
- •Low body temperature (hypothermia)
- •Pancreatitis (inflammation of the pancreas)
- •Metabolic syndrome (a mix of belly fat, low 'good' cholesterol, high fats in blood, high blood pressure, and high blood sugar)
- •Fever, flu-like symptoms, sore throat, or other infection with very low white blood cells (agranulocytosis)
- •Bowel obstruction
- •High levels of muscle enzyme (creatine phosphokinase) in blood
- •Severe rash with blisters or red spots
- •Very bad allergic reaction (anaphylactic shock) that makes it hard to breathe or causes shock
- •Quick swelling of skin (around eyes, lips, throat) (angioedema)
- •Severe blistering on skin, mouth, eyes, or genitals (Stevens-Johnson Syndrome)
- •Unusual release of a hormone that controls urine
- •Muscle breakdown and pain (rhabdomyolysis)
- •Rash with irregular red patches (erythema multiforme)
- •Quick red skin areas with small pus-filled blisters (Acute Generalized Exanthematous Pustulosis (AGEP))
- •Severe, sudden allergic reaction with fever, skin blisters, and peeling skin (Toxic Epidermal Necrolysis)
- •Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) (flu-like symptoms, rash, fever, swollen lymph nodes, and bad blood test results)
- •Withdrawal symptoms in babies if mother used Quetiapine Krka during pregnancy
- •Stroke
- •Heart muscle disease (cardiomyopathy)
- •Heart muscle inflammation (myocarditis)
- •Blood vessel inflammation (vasculitis), often with small red/purple spots on skin
Important Warnings
- Do not take if you are allergic to quetiapine or any other ingredients in this medicine.
- Do not take with certain medicines for HIV, fungal infections (azoles), bacterial infections (erythromycin or clarithromycin), or depression (nefazodone).
- Seek immediate medical help if you experience fever, severe muscle stiffness, sweating, or decreased consciousness (a serious condition called Neuroleptic Malignant Syndrome).
- Tell your doctor right away if you have uncontrolled movements, especially of your face or tongue.
- Inform your doctor if you feel very dizzy or drowsy, as this can increase the risk of falls, especially for older patients.
Show 10 more warnings
- Report any seizures to your doctor.
- Seek medical help for a prolonged, painful erection (priapism).
- Contact your doctor immediately if you experience fast or irregular heartbeat, palpitations, breathing difficulties, chest pain, or unusual tiredness. Your heart may need to be checked.
- Tell your doctor as soon as possible if you have a fever, flu-like symptoms, sore throat, or other infection, as this could mean you have very few white blood cells, which may require stopping Quetiapine Krka and needing treatment.
- Report constipation and lasting stomach pain, or constipation that doesn't improve with treatment, as this can lead to a serious bowel blockage.
- If you feel depressed and have thoughts of harming yourself or suicide, contact your doctor or the nearest hospital immediately.
- Stop using Quetiapine Krka and seek immediate medical help if you notice severe skin reactions, such as widespread rash with blisters, peeling skin, or flu-like symptoms with rash and fever.
- Quetiapine Krka should not be used by children or adolescents under 18 years of age.
- If you are pregnant or breastfeeding, or planning to be, talk to your doctor before using this medicine. Do not use Quetiapine Krka during pregnancy or breastfeeding unless your doctor advises it.
- This medicine can make you feel sleepy. Do not drive or operate machinery until you know how it affects you.