Quetiapin Krka
Quetiapin Krka is a medicine for mental health conditions like bipolar disorder, mania, and schizophrenia.
Form
depottabletti
Strength
50 mg
Active Ingredient
Quetiapine hemifumarate
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
Your doctor will tell you how much to take. The usual daily dose is between 150 mg and 800 mg.
Method
Take the tablets once a day, whole, with water. Do not break, chew, or crush them. Take without food, at least 1 hour before a meal or at bedtime. Do not drink grapefruit juice.
Important
The usual maximum daily dose is 800 mg.
Possible Side Effects
COMMON
- •Dizziness (may lead to falls), headache, dry mouth
- •Drowsiness (may lead to falls)
- •Withdrawal symptoms (insomnia, nausea, headache, diarrhea, vomiting, irritability) if stopping treatment suddenly
- •Weight gain
- •Abnormal muscle movements (difficulty starting movements, shaking, restlessness, muscle stiffness without pain)
- •Changes in blood fat levels (triglycerides, total cholesterol)
- •Fast heartbeat, palpitations
- •Constipation, indigestion
- •Weakness
- •Swelling of hands or feet
- •Low blood pressure (especially when standing up), may cause dizziness or faintness (may lead to falls)
- •High blood sugar
- •Blurred vision
- •Abnormal dreams and nightmares
- •Increased appetite
- •Irritability
- •Speech and language problems
- •Suicidal thoughts and worsening depression
- •Shortness of breath
- •Vomiting (mainly in elderly)
- •Fever
- •Changes in blood thyroid hormone levels
- •Decrease in certain types of white blood cells
- •Increase in blood liver enzymes
- •Increase in prolactin hormone in blood (can cause breast swelling, unexpected milk production, missed or irregular periods)
RARE
- •Seizures (epilepsy)
- •Allergic reactions (hives, swelling of skin and mouth)
- •Restless legs syndrome
- •Difficulty swallowing
- •Sexual dysfunction
- •Worsening diabetes
- •Changes in the heart's electrical activity (QT prolongation on ECG)
- •Slower heart rate (especially at start of treatment), possibly with low blood pressure and fainting
- •Difficulty urinating, fainting (may lead to falls)
- •Nasal congestion
- •Decrease in red blood cells, decrease in blood sodium levels
- •Confusion
- •Yellow skin and eyes (jaundice)
- •Liver inflammation (hepatitis)
- •Blood clots in veins (especially in legs), with symptoms like swelling, pain, redness; may travel to lungs causing chest pain, breathing difficulties
- •Sleepwalking, sleep talking, or other activities during sleep
- •Low body temperature (hypothermia)
- •Pancreatitis
- •Metabolic syndrome (abdominal obesity, low 'good' cholesterol, high triglycerides, high blood pressure, high blood sugar)
- •Combination of fever, flu-like symptoms, sore throat, or other infection, and very low white blood cell count (agranulocytosis)
- •Bowel obstruction
- •Increase in creatine phosphokinase in blood (substance from muscles)
- •Severe allergic reaction (anafylactic shock), causing breathing difficulties or shock
- •Rapid swelling under the skin, usually around the eyes, lips, or throat (angioedema)
- •Abnormal secretion of hormone regulating urine volume
- •Muscle fiber breakdown and muscle pain (rhabdomyolysis)
- •Heart muscle disease (cardiomyopathy)
- •Heart muscle inflammation (myocarditis)
- •Inflammation of blood vessels (vasculitis), often with small red or purple skin rash
Important Warnings
- Do not take this medicine if you are allergic to quetiapine or any other ingredients.
- Do not use with certain HIV medications, antifungal medicines, erythromycin, clarithromycin, or nefazodone.
- Contact a doctor immediately if you experience fever, severe muscle stiffness, sweating, or changes in consciousness (neuroleptic malignant syndrome).
- Tell your doctor immediately if you have uncontrolled movements, especially in your face or tongue.
- Tell your doctor immediately if you feel dizzy or very drowsy (this can increase the risk of falls).
Show 7 more warnings
- Contact your doctor if you have thoughts of harming yourself or suicide, or if your depression worsens.
- Stop using the medicine and contact a doctor immediately if you develop severe skin reactions like blisters or peeling skin.
- Be careful with alcohol and grapefruit juice; they can affect how the medicine works and cause drowsiness.
- Do not drive or operate machinery if you feel drowsy.
- Weight gain may occur, so monitor your weight regularly.
- This medicine should not be given to children or adolescents under 18 years of age.
- Do not stop taking the medicine suddenly, as this can cause withdrawal symptoms like insomnia, nausea, headache, or irritability.