Qsiva

Qsiva is a medicine that combines two active ingredients, phentermine and topiramate, to help reduce appetite and promote weight loss when used with a low-calorie diet and exercise.

Form
säädellysti vapauttava kapseli, kova
Strength
15 mg / 92 mg
Active Ingredient
Phentermine hydrochloride
Manufacturer
VIVUS BV

How to Use

Dosage

Your doctor will start you on a low dose, typically 1 Qsiva 3.75 mg/23 mg capsule once a day for 14 days, then usually 1 Qsiva 7.5 mg/46 mg capsule once a day. Your doctor will adjust your dose if needed.

Method

Swallow capsules whole with a glass of water or other sugar-free drink in the morning. Do not crush or chew them. You can take them with or without food.

Important

The maximum daily dose is 1 Qsiva 15 mg/92 mg capsule once a day.

Possible Side Effects

COMMON
  • •Dry mouth
  • •Constipation
  • •Tingling, burning, or numbness (abnormal sensations)
  • •Loss of appetite
  • •Changes in taste
  • •Sleep problems
  • •Depression
  • •Anxiety
  • •Irritability
  • •Headache
  • •Dizziness
  • •Trouble concentrating
  • •Tiredness
  • •Memory problems
  • •Reduced skin sensitivity
  • •Blurred vision
  • •Dry eyes
  • •Feeling of fast heartbeat
  • •Nausea
  • •Diarrhea
  • •Stomach pain
  • •Digestive problems
  • •Hair loss
  • •Thirst
  • •Nervousness
RARE
  • •Urinary tract infection
  • •Low red blood cells (anemia)
  • •Low potassium in blood
  • •Low blood sugar
  • •Swelling from too much fluid in tissues
  • •Dehydration
  • •Increased appetite
  • •Decreased or increased sex drive
  • •Mood changes, emotional problems
  • •Agitation, restlessness
  • •Confusion, mood swings, lack of interest
  • •Sleep problems, including bad dreams or nightmares
  • •Crying, stress, anger
  • •Panic attack, paranoia
  • •Partial or total memory loss
  • •Drowsiness, sluggishness
  • •Uncontrolled trembling
  • •Thinking or speech problems
  • •Changed taste
  • •Migraine
  • •Overactivity
  • •Nerve problems (not in brain or spinal cord)
  • •Fainting
  • •Restless legs syndrome
  • •Unusual coordination
  • •Changed sense of smell
  • •Eye pain, eyelid twitching
  • •Unpleasant light sensitivity in eyes
  • •Flashing lights in vision
  • •Double vision, itchy eyes
  • •Ringing in ears
  • •Increased heart rate
  • •Redness
  • •Low or high blood pressure
  • •Cough, nosebleed
  • •Breathing difficulties
  • •Sore throat and voice box
  • •Blocked sinuses or nose, post-nasal drip
  • •Gas, burping
  • •Heartburn, vomiting
  • •Itching, hives, rash, skin redness, dry skin
  • •Increased sweating, acne, unusual body odor
  • •Unusual hair texture
  • •Arm and leg pain, muscle pain, back pain, joint pain
  • •Muscle cramps, muscle weakness, muscle twitching
  • •Kidney stones
  • •Frequent urination (not increased volume), trouble starting urination
  • •Frequent nighttime urination
  • •Erection problems
  • •Menstrual problems
  • •Weakness, unusual sensations
  • •Swelling of arms and/or legs due to fluid buildup
  • •Increased energy, chest pain, cold or hot sensations
  • •Decreased blood levels of bicarbonate or potassium
  • •Abnormal liver function tests
  • •Reduced creatinine clearance (a measure of kidney function)
  • •Respiratory infection (e.g., flu, bronchitis, sinusitis)
  • •Yeast infection (Candida)
  • •Ear infection
  • •Excess body acid due to metabolic disorder, gout
  • •Suicidal thoughts, aggression
  • •Inability to feel pleasure (including low motivation), grief
  • •Teeth grinding, aversion to food
  • •Hallucinations, confusion about time and place
  • •Stammering
  • •Pins and needles sensation
  • •Increased tear production
  • •Increased eye pressure, bleeding in the eye's conjunctiva
  • •Deafness, earache
  • •Heart rhythm disorder (very rapid activity in upper heart chambers), irregular heartbeat
  • •Deep vein thrombosis (a type of blood clot)
  • •Dry throat, runny nose
  • •Bad breath, gum pain, tongue inflammation, burning sensation on tongue
  • •Hemorrhoids, irregular bowel movements
  • •Gallstones or related diseases
  • •Gallbladder inflammation
  • •Brittle nails
  • •Muscle stiffness
  • •Unusual urine smell
  • •Walking problems
  • •Falls
  • •Increased creatinine in blood
  • •Increased blood sugar levels
  • •Viral stomach and intestinal inflammation
  • •Hypersensitivity (general allergic reaction)
  • •Excessive talkativeness
  • •Suicide attempt
  • •Seizures
  • •Pain in one or more nerves
  • •Temporary blindness
  • •Dilated pupils
  • •Lens clouding (cataract)
  • •An eye disease where the center of the retina breaks down, potentially leading to central vision loss
  • •Hearing loss, fluid buildup in the middle ear
  • •Heart failure
  • •Nasal polyps, acute lung failure
  • •Difficulty swallowing, discomfort in mouth, gagging
  • •Severe allergic reaction causing swelling of the face or throat
  • •Acute kidney injury
  • •Feeling of a foreign object
  • •Lowered blood sugar levels
  • •Increased blood levels of glycosylated hemoglobin, thyroid hormone, triglycerides
  • •Eye inflammation (uveitis) with symptoms like eye redness, pain, light sensitivity, watery eyes, small spots in visual field, or blurred vision

Important Warnings

  • Do not take if you are allergic to phentermine, topiramate, or any other ingredient in Qsiva, or to similar medicines called sympathomimetic amines (used for asthma, nasal congestion, or eye problems).
  • Do not take if you are pregnant or can become pregnant and are not using highly effective birth control. Qsiva can harm an unborn baby.
  • Do not take if you have used certain depression or Parkinson's disease medicines (called MAO inhibitors) in the last 14 days.
  • Do not take other medicines that help you lose weight.
  • Tell your doctor immediately if you have any sudden changes in mood, behavior, or suicidal thoughts.
Show 9 more warnings
  • Inform your doctor if you have heart problems, as Qsiva can increase your heart rate or may not be suitable if you've had recent heart issues.
  • Drink plenty of water daily to help prevent kidney stones, which Qsiva can increase the risk of.
  • Stop taking Qsiva and contact your doctor immediately if you experience sudden blurry vision, eye pain, or other serious eye problems.
  • Tell your doctor if you have too much acid in your blood.
  • Tell your doctor if you have kidney problems, liver problems, or an overactive thyroid, as Qsiva might not be suitable for you.
  • Avoid alcohol while taking Qsiva, as it may increase side effects.
  • Be careful when driving or operating machinery until you know how Qsiva affects you, as it can cause dizziness or blurred vision.
  • If you have a sugar intolerance (saccharose), talk to your doctor before taking Qsiva.
  • Some Qsiva strengths contain tartrazine and sunset yellow, which may cause allergic reactions.