Propofol-Lipuro
Propofol-Lipuro is a medicine used to make you unconscious (sleep) for surgery or other procedures, or to make you drowsy but not fully asleep.
Form
injektio/infuusioneste, emulsio
Strength
5 mg/ml
Active Ingredient
Propofol
Manufacturer
B. Braun Melsungen AG
How to Use
Dosage
Your doctor will decide the right dose for you based on your age, weight, and health, and will monitor your vital signs.
Method
It is given as an injection or infusion into a vein by a trained professional.
Important
It is given for a maximum of 1 hour.
Possible Side Effects
COMMON
- •Pain at the injection site during the first injection.
- •Low blood pressure.
- •Slow heartbeat.
- •Short pauses in breathing.
- •Headache during recovery.
- •Feeling sick or vomiting during recovery.
- •Blood clots in veins or vein inflammation at the injection site.
RARE
- •Seizures like epilepsy.
- •Allergic reactions, including swelling of the face, tongue, or throat, wheezing, red skin, and low blood pressure.
- •Unconsciousness after surgery.
- •Fluid buildup in the lungs (pulmonary edema).
- •Pancreatitis (inflammation of the pancreas).
- •Uncontrolled sexual behavior during recovery.
- •Abnormal urine color after long-term propofol use.
- •Fever after surgery.
- •Tissue damage if the medicine is accidentally injected outside a vein.
- •Propofol infusion syndrome (a combination of muscle breakdown, acid buildup in blood, high potassium, high fat levels in blood, abnormal heart rhythm, enlarged liver, irregular heartbeat, kidney and heart failure). Some cases have been fatal.
- •Hepatitis (liver inflammation), acute liver failure (symptoms include yellow skin/eyes, itching, dark urine, abdominal pain, loss of appetite).
- •Involuntary movements.
- •Abnormal good mood.
- •Drug misuse and dependence.
- •Heart failure.
- •Cardiac arrest.
- •Shallow breathing.
- •Prolonged, painful erection.
- •Pain and/or swelling at the injection site if accidentally injected outside a vein.
- •Muscle breakdown (rhabdomyolysis) has been reported in rare cases when higher than recommended doses were used for sedation in intensive care.
Important Warnings
- Do not use if you are allergic to propofol, soy, peanuts, or any other ingredient in this medicine.
- Not recommended for long-term sedation in children or for sedation in intensive care.
- Tell your doctor if you have serious head injuries, mitochondrial disease, fat metabolism disorders, low blood volume, low protein levels, heart, kidney, or liver problems, high pressure in your head, breathing difficulties, or epilepsy.
- Do not drive or operate machinery for some time after receiving this medicine.
- Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine should not be used during pregnancy unless absolutely necessary. If breastfeeding, stop for 24 hours after treatment.