Prohance
ProHance is a contrast agent used in magnetic resonance imaging (MRI) to help doctors see your brain, spinal cord, surrounding tissues, or your entire body (if you are an adult) more clearly.
Form
injektioneste, liuos, esitäytetty ruisku
Strength
279.3 mg/ml
Active Ingredient
Gadoteridol
Manufacturer
Bracco International B.V.
How to Use
Dosage
The typical dose is 0.2 ml per kilogram of body weight for adults and children for brain and spinal cord scans, and for whole-body scans in adults. In some cases, the dose for brain and spinal cord scans may be increased to 0.6 ml per kilogram for adults.
Method
ProHance is given as an injection into a vein by a healthcare professional before your scan.
Important
You will usually receive only one dose for your scan. If you have severe kidney problems, or are a newborn or infant, you should only receive one dose, and not another dose for at least 7 days.
Possible Side Effects
COMMON
- •Nausea (feeling sick)
RARE
- •Headache, changes in sensation (tingling, numbness), drowsiness, taste changes
- •Low blood pressure, hot flashes
- •Dry mouth, vomiting
- •Itching, skin rash, hives
- •Pain at the injection site
- •Injection site reaction
- •Fatigue, feeling weak
- •Increased heart rate
- •Allergic reactions (symptoms usually include throat tightness, throat irritation, breathing difficulties, chest discomfort, feeling hot, difficulty swallowing, burning sensation, swollen throat, and low blood pressure)
- •Restlessness, anxiety
- •Seizures, abnormal movement coordination, decreased mental performance
- •Watery eyes
- •Ringing in the ears (tinnitus)
- •Changes in heart rhythm
- •Throat spasm, shortness of breath, runny nose, cough, temporary stop in breathing, wheezing
- •Abdominal pain, swollen tongue, itchy mouth, gum inflammation, diarrhea
- •Facial swelling
- •Muscle stiffness
- •Chest pain, fever
- •Coma, loss of consciousness
- •Vasovagal reaction (common symptoms include nausea, dizziness, and heavy sweating; in severe cases, symptoms may include paleness, heavy sweating, slow heart rate, and possible loss of consciousness. Other symptoms may be fear or anxiety, restlessness, weakness, and excessive salivation).
- •Cardiac arrest
- •Respiratory arrest, fluid in the lungs
- •Angioedema (symptoms include swelling of the face, tongue, or throat, difficulty swallowing, hives, and breathing difficulties)
- •Kidney failure
- •Nephrogenic systemic fibrosis (causes hardening of the skin and can affect soft tissues and internal organs) has been reported, mostly in patients who also received other gadolinium-containing contrast agents with ProHance.
Important Warnings
- Do not use ProHance if you are allergic to gadoteridol or any other ingredients in this medicine.
- Tell your doctor if your kidneys do not work well.
- Tell your doctor if you recently had or will soon have a liver transplant.
- Your doctor might check your kidney function with a blood test, especially if you are 65 or older.
- Tell your doctor if you have or have had allergies.
Show 3 more warnings
- Tell your doctor if you have had epilepsy or a brain injury.
- If you are pregnant, think you might be pregnant, or are planning to have a baby, talk to your doctor. ProHance should not be used during pregnancy unless absolutely necessary.
- If you are breastfeeding or plan to start breastfeeding, your doctor will discuss whether you should continue or stop breastfeeding for 24 hours after using ProHance.