Procren Depot PDS
Procren Depot PDS is a synthetic hormone that reduces the production of testosterone and estrogen, used to treat various conditions like prostate cancer, endometriosis, breast cancer, uterine fibroids, and early puberty in children.
Form
injektiokuiva-aine ja liuotin suspensiota varten, esitäytetty ruisku
Strength
3.75 mg
Active Ingredient
Leuprorelin acetate
Manufacturer
AbbVie Oy
How to Use
Dosage
The exact dose varies depending on your condition and is decided by your doctor. It is typically given as a single injection once a month or every three months.
Method
This medicine is given as an injection under the skin (subcutaneous) by a doctor or nurse.
Important
This is not a daily medicine. Your doctor will determine the correct dose and frequency for your specific treatment plan, usually once a month or every three months.
Possible Side Effects
COMMON
- •Injection site reactions (pain, bruising, inflammation, lump)
- •Headache
- •Dizziness
- •Nausea and vomiting
- •Rash
- •Acne
- •Hot flushes
- •Mood changes (when used for a long time)
- •Depression (when used for a long time)
- •Shortness of breath
- •Excessive sweating
- •Muscle and joint pain
- •Swelling (fluid retention)
- •Weakness and fatigue
- •In men: Testicular shrinkage
- •In men: Erectile dysfunction
- •In men: Changes in heart's electrical activity (EKG)
- •In women: Vaginal infection
- •In women: Decreased sexual desire
- •In women: Breast pain and tenderness
- •In women: Breast size reduction
- •In women: Vaginal dryness
- •Abdominal pain or cramps (children)
- •Vaginal bleeding, spotting, or discharge (girls)
RARE
- •Mood changes (when used for a short time)
- •Depression (when used for a short time)
- •Weight changes
- •Vision problems
- •Chest pressure or discomfort
- •Trouble sleeping
- •Severe allergic reaction (anaphylaxis), including fever, rash, itching, or breathing difficulty
- •Muscle stiffness
- •Ringing or buzzing in the ears (tinnitus)
- •Hearing loss
- •Increased body hair
- •Anemia or changes in blood cells
- •Changes in heart's electrical activity (EKG) or chest pain due to poor blood flow to the heart (ischemia)
- •Fast heart rate
- •High blood pressure
- •Numbness or tingling sensations
- •Seizures
- •Loss of appetite
- •Diarrhea
- •Changes in appetite
- •Thirst
- •Constipation
- •Mouth sores or dry mouth
- •Itching or unspecified skin issues
- •Hair loss or nail problems
- •Abnormal liver tests (elevated transaminases or phosphatases)
- •High triglycerides, uric acid, or potassium levels
- •Back or bone pain
- •Urinary problems (difficulty, increased urge, blood in urine, elevated urea)
- •Pneumonia
- •In men: Breast enlargement
- •In women: Painful intercourse or irritability
- •Psychological symptoms like crying, irritability, restlessness, anger, aggressive behavior
- •Pituitary gland changes (risk of bleeding or stroke)
- •Increased pressure in the head (idiopathic intracranial hypertension) causing severe headache, double vision, or ringing in ears
- •Lung disease (interstitial)
- •Severe liver damage or fatty liver (men)
- •Severe skin reactions including rashes, blisters, and peeling skin (like Stevens-Johnson syndrome)
Important Warnings
- Do not use if you are allergic to leuprorelin or any other ingredients in this medicine.
- Do not use if you are pregnant, trying to become pregnant, or breastfeeding.
- Do not use if you have unexplained vaginal bleeding.
- Stop using the medicine and contact your doctor immediately if you experience severe allergic reactions like difficulty breathing, wheezing, dizziness, swelling, or rash.
- Tell your doctor if you feel depressed, as depression has been reported in some patients using this medicine.
Show 4 more warnings
- Contact a doctor immediately if you or your child experience severe or persistent headaches, vision problems, or ringing in the ears.
- Stop taking this medicine and seek immediate medical attention if you develop severe skin rashes, blisters, or peeling skin (like Stevens-Johnson syndrome).
- This medicine may increase the risk of heart rhythm problems. Tell your doctor if you have heart conditions or take medicines for them.
- If you have high blood sugar, diabetes, or high cholesterol, your doctor will monitor you closely.