Primovist
Primovist is a contrast agent used in liver MRI scans to help doctors see and diagnose changes in your liver.
Form
injektioneste, liuos, esitäytetty ruisku
Strength
0.25 mmol/ml
Active Ingredient
Gadoxetate disodium
Manufacturer
Bayer Oy
How to Use
Dosage
The recommended dose is 0.1 ml of Primovist per kilogram of body weight.
Method
Primovist is given into a vein with a small needle just before your MRI scan. You will be observed for at least 30 minutes after the injection.
Important
Only one dose is given per examination. Allow at least 7 days before a possible next injection.
Possible Side Effects
COMMON
- •Headache
- •Nausea
RARE
- •Dizziness
- •Numbness and tingling
- •Changes in taste and smell
- •Redness
- •Increased blood pressure
- •Breathing difficulties
- •Vomiting
- •Dry mouth
- •Rash
- •Severe itching all over the body or in the eyes
- •Back pain, chest pain
- •Reactions at the injection site (like redness, coldness, irritation, or pain)
- •Feeling of warmth
- •Chills
- •Fatigue
- •Unusual feeling or general discomfort
- •Inability to sit or stand still
- •Uncontrolled shaking
- •Heart palpitations
- •Irregular heartbeat
- •Unpleasant feeling in the mouth
- •Increased saliva production
- •Red rash with bumps or spots
- •Increased sweating
- •Fast heart rate
- •Restlessness
- •Low blood pressure
- •Swelling of the tongue, throat, or face
- •Runny nose, sneezing, cough
- •Red, watery, and itchy eyes
- •Abdominal pain
- •Hives
- •Reduced skin sensation or sensitivity, itching, paleness
Important Warnings
- Do not use Primovist if you are allergic to disodium gadoxetate or any other ingredient in this medicine.
- Tell your doctor if you have or have had asthma or allergies like hay fever or hives.
- Tell your doctor if you have had an allergic reaction to a contrast agent before.
- Tell your doctor if you have reduced kidney function.
- If you have severe kidney problems or have recently had a liver transplant, Primovist should be avoided as it can cause a severe hardening of the skin and connective tissues (NSF).
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- Tell your doctor if you have severe heart or blood vessel disease.
- Tell your doctor if you have low potassium levels in your blood.
- Tell your doctor if you or a family member have had problems with your heart's electrical rhythm (long QT syndrome).
- Tell your doctor if your heart rhythm has changed after using medicines.
- Tell your doctor if you have a pacemaker or any iron-containing implants or clips in your body.
- Tell your doctor if you are pregnant or planning to become pregnant, as Primovist should not be used during pregnancy unless absolutely necessary.
- Tell your doctor if you are breastfeeding or plan to start. Your doctor will advise whether to continue or stop breastfeeding for 24 hours after using Primovist.