Prednisolon
Prednisolone is a corticosteroid medicine that reduces inflammation and helps with allergy symptoms, like those from rheumatic conditions.
Form
tabletti
Strength
40 mg
Active Ingredient
Prednisolone
Manufacturer
Orifarm Healthcare A/S
How to Use
Dosage
Your doctor will decide your dose, and you should follow their instructions; treatment usually starts with a higher dose that is then lowered to a maintenance dose.
Method
Prednisolone tablets are taken by mouth once a day in the morning between 7-9 AM to disturb your body's natural hormone production as little as possible.
Important
Your doctor will determine your maximum daily dose. Doses over 15 mg per day are considered high and require special monitoring.
Possible Side Effects
COMMON
- •Increased risk of infections, including fungal infections on skin and mouth.
- •Changes in white blood cell count (can be lower or higher).
- •Adrenal gland problems, Cushing's syndrome (e.g., round face, weight gain), changes in hormone levels.
- •High cholesterol, high blood fats, body holding onto water (swelling), low potassium.
- •Worsening heart failure, high blood pressure.
- •Worsening of inflammatory bowel diseases (like colitis or diverticulitis).
- •Acne, thin skin, poor wound healing, skin inflammation, bruises, facial redness, sweating.
- •Osteoporosis (weak bones), muscle weakness.
- •Needing to urinate often at night.
RARE
- •Mental problems (e.g., feeling overly happy, trouble sleeping, mood changes, depression).
- •High eye pressure (glaucoma), cloudy lens (cataract), blurred vision.
- •Blood clots, heart problems (e.g., heart attack, slow heartbeat, problems with heart muscle).
- •Stomach ulcers, bleeding in the stomach/bowel, pancreatitis.
- •Kidney stones, acute kidney crisis (a serious problem for people with scleroderma).
- •Severe skin reactions, bone death, dementia, prolonged coma, bulging eyes.
- •Can affect children's growth (with long-term use).
- •Allergic reactions (e.g., skin rash).
Important Warnings
- You must stop Prednisolone treatment slowly and gradually, as your body's own hormone production might have weakened after long-term use.
- Contact your doctor if you experience fever or stress during treatment, as your dose may need to be adjusted.
- If you have diabetes, your insulin dose needs to be carefully monitored during Prednisolone treatment.
- Do not get live vaccines if you are taking high doses (over 15 mg/day) of Prednisolone.
- If you have scleroderma, talk to your doctor, as daily doses over 15 mg can increase the risk of a serious kidney problem.
Show 6 more warnings
- Prednisolone can cause mood changes or depression; contact your doctor immediately if you suspect depression or have suicidal thoughts.
- Contact your doctor if you experience blurred vision or other vision problems.
- Always tell your doctor about all other medicines you are taking, as Prednisolone can interact with them.
- Ask your doctor for advice if you are pregnant, breastfeeding, or planning to become pregnant, as Prednisolone can affect the baby and pass into breast milk.
- Long-term Prednisolone treatment can cause menstrual problems and reduce sperm production.
- Prednisolone 5 mg tablets contain lactose and castor oil, which can cause stomach upset and diarrhea.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Consider the risk of adverse effects of cortisone treatment. (updated 10.11.2025)