Posaconazole STADA
Posaconazole Stada is an antifungal medicine used to prevent and treat various fungal infections.
Form
oraalisuspensio
Strength
40 mg/ml
Active Ingredient
Posaconazole
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
The usual dose is 200 mg (one 5 ml spoon) four times a day. Your doctor may change your dose or prescribe 400 mg (two 5 ml spoons) twice a day. For preventing fungal infections, the usual dose is 200 mg three times a day.
Method
Take the medicine with food or a nutritional supplement, or right after. Shake the bottle well for 5-10 seconds before use.
Important
The maximum daily dose is usually 800 mg. Do not exceed the dose prescribed by your doctor.
Possible Side Effects
COMMON
- •Abnormal salt levels in blood tests (symptoms include confusion and weakness).
- •Abnormal skin sensations such as numbness, tingling, itching, crawling, stinging, or burning.
- •Headache.
- •Low potassium levels in blood tests.
- •Low magnesium levels in blood tests.
- •High blood pressure.
- •Loss of appetite, stomach pain or discomfort, gas, dry mouth, changes in taste.
- •Heartburn (a burning sensation rising in the throat or chest).
- •Low levels of neutrophils, a type of white blood cell (neutropenia), which can increase the risk of infections.
- •Fever.
- •Feeling weak, dizziness, tiredness, or drowsiness.
- •Rash.
- •Itching.
- •Constipation.
- •Unpleasant feeling in the rectum.
RARE
- •Anemia (symptoms include headache, tiredness, dizziness, shortness of breath, or paleness, and low hemoglobin levels in blood tests).
- •Low platelet count (thrombocytopenia) in blood tests, which can lead to bleeding.
- •Low white blood cell count (leukopenia) in blood tests, which can increase the risk of infections.
- •High levels of eosinophils (eosinophilia), a type of white blood cell, which may be related to inflammation.
- •Inflammation of blood vessels.
- •Heart rhythm problems.
- •Seizures.
- •Nerve damage (neuropathy).
- •Irregular heartbeat on an ECG, heart palpitations, slow or fast heart rate, high or low blood pressure.
- •Low blood pressure.
- •Pancreatitis (inflammation of the pancreas), which can cause severe stomach pain.
- •Lack of oxygen to the spleen (splenic infarction), which can cause severe stomach pain.
- •Severe kidney problems (symptoms may include more or less urination than normal and abnormal urine color).
- •High blood creatinine levels in blood tests.
- •Cough, hiccups.
- •Nosebleeds.
- •Severe sharp chest pain when breathing in (pleuritic pain).
- •Swollen lymph nodes (lymphadenopathy).
- •Reduced sensitivity to touch, especially on the skin.
- •Tremors.
- •High or low blood sugar levels.
- •Blurred vision, sensitivity to light.
- •Hair loss.
- •Mouth sores.
- •Chills, general feeling of being unwell.
- •Pain, back pain or neck pain, arm or leg pain.
- •Fluid retention in the body (swelling).
- •Menstrual disorders (abnormal vaginal bleeding).
- •Insomnia (difficulty sleeping).
- •Complete or partial inability to speak.
- •Swelling of the mouth.
- •Abnormal dreams or difficulty sleeping.
- •Coordination or balance problems.
- •Inflammation of mucous membranes.
- •Nasal congestion.
- •Difficulty breathing.
- •Unpleasant feeling in the chest.
- •Feeling of abdominal bloating.
- •Mild, moderate, or severe nausea, vomiting, severe stomach pain, and diarrhea (usually caused by a virus), stomach pain.
- •Burping.
- •Feeling nervous.
RARE
- •Pneumonia (symptoms include shortness of breath and discolored phlegm).
- •High blood pressure in the lung arteries (pulmonary hypertension), which can cause serious damage to the lungs and heart.
- •Unusual blood clotting, prolonged bleeding.
- •Severe allergic reactions, such as widespread blistering rash and skin peeling.
- •Mental disorders, such as visual or auditory hallucinations.
- •Fainting.
- •Difficulty thinking or speaking, involuntary jerky movements, especially in the hands.
- •Stroke (symptoms include pain, weakness, numbness, or tingling in the limbs).
- •Blind spot or dark spot in the field of vision.
- •Heart failure or heart attack, which can lead to cardiac arrest and death, heart rhythm problems, and sudden death.
- •Blood clot in the legs (deep vein thrombosis) (symptoms include severe pain or swelling in the calves).
- •Blood clot in the lungs (pulmonary embolism) (symptoms include shortness of breath or pain when breathing).
- •Stomach or intestinal bleeding (symptoms include vomiting blood or blood in stools).
- •Bowel obstruction (ileus), especially in the lower part of the small intestine. The blockage prevents food from passing into the lower bowel. Symptoms include abdominal bloating, vomiting, severe constipation, loss of appetite, and severe stomach pain.
- •Hemolytic uremic syndrome (breakdown of red blood cells, also called hemolysis), which may also involve kidney failure.
- •Pancytopenia (abnormal deficiency of all blood cells: red, white, and platelets) in blood tests.
- •Widespread purple-red discolorations on the skin (thrombotic thrombocytopenic purpura).
- •Swelling of the face or tongue.
- •Depression.
- •Double vision.
- •Breast pain.
- •Adrenal gland dysfunction, which can cause weakness, tiredness, loss of appetite, skin discoloration.
- •Pituitary gland dysfunction, which can reduce the levels of hormones affecting male and female reproductive organs in the blood.
- •Hearing problems.
- •Pseudoaldosteronism, which leads to high blood pressure and low potassium levels (found in blood tests).
- •Confused state reported by some patients after taking posaconazole.
- •Skin redness.
Important Warnings
- Do not take this medicine if you are allergic to posaconazole or any other ingredient in this medicine.
- Do not take this medicine if you are taking certain other medicines such as terfenadine, astemizole, cisapride, pimozide, halofantrine, quinidine, ergot alkaloids (like ergotamine or dihydroergotamine), or "statins" (like simvastatin, atorvastatin, or lovastatin).
- Do not take this medicine if you have just started or are slowly increasing your dose of venetoclax for chronic lymphocytic leukemia (CLL).
- Tell your doctor if you have ever had an allergic reaction to another antifungal medicine.
- Tell your doctor if you have or have had liver problems. You may need blood tests during treatment.
Show 11 more warnings
- If you get severe diarrhea or vomiting, tell your doctor right away as it may make this medicine less effective.
- Tell your doctor if you have an abnormal heart rhythm on an ECG, known as a prolonged QTc interval.
- Tell your doctor if you have heart muscle weakness or heart failure.
- Tell your doctor if you have a very slow heart rate.
- Tell your doctor if you have an irregular heartbeat.
- Tell your doctor if you have changes in your blood potassium, magnesium, or calcium levels.
- Tell your doctor if you are taking vincristine, vinblastine, or other vinca alkaloids (medicines for cancer treatment).
- Avoid direct sunlight during treatment. Protect your skin with clothing and high SPF sunscreen, as your skin may become sensitive to UV rays.
- Posaconazole Stada should not be used in children and adolescents (17 years and younger).
- Do not breastfeed while taking Posaconazole Stada, as small amounts of the medicine may pass into breast milk.
- This medicine may cause dizziness, drowsiness, or blurred vision, which can affect your ability to drive or use machines. If you experience these symptoms, do not drive or use machines and contact your doctor.