Pomalidomide Glenmark
Pomalidomide Glenmark is a medicine used to treat a type of cancer called multiple myeloma in adults by slowing down cancer cell growth and helping the body's immune system.
Form
kapseli, kova
Strength
4 mg
Active Ingredient
Pomalidomide
Manufacturer
Glenmark Arzneimittel GmbH
How to Use
Dosage
The usual starting dose is 4 mg once a day.
Method
Swallow the capsules whole with water. You can take them with or without food. Take your capsule at about the same time each day. Do not break, open, or chew the capsules.
Important
The maximum daily dose is 4 mg.
Possible Side Effects
COMMON
- •Fever, chills, sore throat, cough, mouth sores, or other signs of infection (due to low white blood cells).
- •Bleeding or bruising easily, including nosebleeds or bleeding in the stomach or intestines (due to low platelet count).
- •Fast breathing, fast heartbeat, fever, chills, very little or no urine, nausea, vomiting, confusion, or passing out (signs of a serious bloodstream infection called sepsis).
- •Severe, long-lasting, or bloody diarrhea (possibly with stomach pain or fever) caused by a specific bacterial infection (Clostridium difficile).
- •Chest pain, or pain and swelling in your legs, especially in your calves (signs of a blood clot).
- •Shortness of breath (due to serious lung infection, pneumonia, heart failure, or blood clot).
- •Swelling of your face, lips, tongue, or throat, making it hard to breathe (signs of a severe allergic reaction like angioedema or anaphylaxis).
- •Certain types of skin cancer (squamous cell carcinoma and basal cell carcinoma) that can cause changes or growths on your skin. Tell your doctor as soon as possible if you notice any skin changes.
- •Hepatitis B returning, causing yellow skin and eyes, dark urine, right-sided stomach pain, fever, nausea, or vomiting.
- •Widespread rash, high body temperature, swollen lymph nodes, and symptoms affecting other organs (signs of severe reactions like DRESS, drug hypersensitivity syndrome, TEN, or SJS).
- •Shortness of breath.
- •Lung infections (pneumonia and bronchitis).
- •Bacterial or viral infections of the nose, sinuses, and throat.
- •Flu-like symptoms (influenza).
- •Low red blood cell count (anemia), causing tiredness and weakness.
- •Low blood potassium, causing tiredness, muscle cramps, muscle pain, fast heartbeat, tingling or numbness, shortness of breath, and mood changes.
- •High blood sugar.
- •Fast and irregular heartbeat (atrial fibrillation).
- •Loss of appetite.
- •Constipation, diarrhea, or nausea.
- •Vomiting.
- •Stomach pain.
- •Lack of energy.
- •Difficulty falling or staying asleep.
- •Dizziness, tremor (shaking).
- •Muscle spasms, muscle weakness.
- •Bone pain, back pain.
- •Numbness, tingling, or burning sensation on the skin, pain in hands or feet (peripheral sensory neuropathy).
- •Body swelling, including arms and legs.
- •Rashes.
- •Urinary tract infection (UTI), which may cause burning when urinating or needing to urinate often.
- •Falls.
- •Bleeding inside the head.
- •Reduced movement or sensation in hands, arms, feet, and legs due to nerve damage (peripheral sensorimotor neuropathy).
- •Skin numbness, itching, and tingling (paresthesia).
- •A spinning sensation in the head (vertigo), which can make it hard to stand or move normally.
- •Fluid retention.
- •Hives (urticaria).
- •Skin itching.
- •Shingles.
- •Heart attack (chest pain spreading to arms, neck, jaw, sweating, shortness of breath, nausea, or vomiting).
- •Chest pain, chest infection.
- •High blood pressure.
- •Low counts of red blood cells, white blood cells, and platelets all at once (pancytopenia), making you more prone to bleeding, bruising, infections, tiredness, weakness, and shortness of breath.
- •Low white blood cell count called lymphopenia (often due to infection).
- •Low blood magnesium, causing tiredness, weakness, muscle cramps, irritability, and potentially low blood calcium (leading to numbness/tingling in hands, feet, or lips, muscle cramps, muscle weakness, dizziness, or confusion).
- •Low blood phosphate, causing muscle weakness, irritability, or confusion.
- •High blood calcium, causing slow reflexes and weak skeletal muscles.
- •High blood potassium, which may cause irregular heartbeats.
- •Low blood sodium, causing tiredness, confusion, muscle twitching, seizures, or coma.
- •High blood uric acid, which can cause a type of joint inflammation called gout.
- •Low blood pressure, causing dizziness or fainting.
- •Mouth pain or dryness.
- •Changes in taste.
- •Abdominal swelling.
- •Confusion.
- •Depression.
- •Loss of consciousness, fainting.
- •Blurred vision (cataract).
- •Kidney damage.
- •Inability to urinate.
- •Abnormal liver test results.
- •Pelvic pain.
- •Weight loss.
RARE
- •Stroke.
- •Liver inflammation (hepatitis), causing itchy skin, yellow skin and eyes (jaundice), pale stools, dark urine, and stomach pain.
- •Breakdown of cancer cells releasing toxic substances into the bloodstream (tumor lysis syndrome), which can lead to kidney problems.
- •Underactive thyroid (hypothyroidism), which can cause symptoms like tiredness, lethargy, muscle weakness, slow heart rate, and weight gain.
Important Warnings
- Pomalidomide Glenmark can cause severe birth defects or death in an unborn baby. Do not take this medicine if you are pregnant, think you might be pregnant, or are planning to become pregnant. You must follow the contraception rules in this leaflet.
- Do not take this medicine if you are allergic to pomalidomide or any other ingredients in it.
- You have a higher risk of getting blood clots in your veins and arteries while taking Pomalidomide Glenmark, especially if you've had them before.
- Tell your doctor if you have had an allergic reaction to similar medicines like thalidomide or lenalidomide.
- Tell your doctor if you have had a heart attack, heart failure, breathing problems, if you smoke, or have high blood pressure or high cholesterol.
Show 5 more warnings
- If you have a lot of tumors, especially in your bone marrow, this medicine can cause a condition called tumor lysis syndrome, where tumors break down and release harmful chemicals into your blood, potentially leading to kidney problems or irregular heartbeats.
- Tell your doctor if you have or have had nerve damage (neuropathy) causing tingling or pain in your hands or feet.
- If you have ever had hepatitis B, this medicine might cause the virus to become active again, leading to a new infection.
- Seek immediate medical help if you get a widespread rash, red skin, high fever, flu-like symptoms, or swollen glands, as these can be signs of serious skin reactions like DRESS, TEN, or SJS.
- Patients taking Pomalidomide Glenmark for multiple myeloma may develop other types of cancer. Your doctor will discuss the benefits and risks with you.