Pomalidomide Glenmark
Pomalidomide Glenmark is used to treat multiple myeloma, a type of cancer, in adults by stopping cancer cell growth and supporting the immune system.
Form
kapseli, kova
Strength
1 mg
Active Ingredient
Pomalidomide
Manufacturer
Glenmark Arzneimittel GmbH
How to Use
Dosage
The usual starting dose is 4 mg once a day. Your doctor may change your dose.
Method
Swallow the capsules whole with water. Do not break, open, or chew the capsules. You can take the medicine with or without food, but take it around the same time each day.
Important
The recommended daily dose is 4 mg. Do not take more than this without your doctor's advice.
Possible Side Effects
COMMON
- •Shortness of breath
- •Lung infections (pneumonia, bronchitis)
- •Nose, sinus, and throat infections
- •Flu-like symptoms
- •Low red blood cell count (anemia) causing tiredness and weakness
- •Low potassium in blood causing weakness, muscle cramps, muscle pain, fast heartbeat, tingling, numbness, shortness of breath, or mood changes
- •High blood sugar
- •Fast and irregular heartbeat (atrial fibrillation)
- •Loss of appetite
- •Constipation
- •Diarrhea
- •Nausea (feeling sick)
- •Vomiting (being sick)
- •Stomach pain
- •Fatigue or lack of energy
- •Difficulty sleeping or waking up
- •Dizziness
- •Tremors
- •Muscle cramps or muscle weakness
- •Bone pain
- •Back pain
- •Numbness, tingling, or burning sensation in skin, pain in hands or feet due to nerve damage (peripheral sensory neuropathy)
- •Swelling in the body, including arms and legs
- •Rashes
- •Urinary tract infection causing burning when urinating or needing to urinate more often
- •Falls
- •Bleeding in the head
- •Reduced movement or sensation in hands, arms, feet, or legs due to nerve damage (peripheral sensorimotor neuropathy)
- •Numbness, itching, and a pins-and-needles sensation in the skin (paresthesia)
- •Spinning sensation in the head (vertigo) that makes it hard to stand or move normally
- •Swelling due to fluid retention
- •Hives (urticaria)
- •Skin itching
- •Shingles
- •Heart attack (chest pain spreading to arms, neck, jaw, sweating, shortness of breath, nausea, or vomiting)
- •Chest pain due to lung or bronchial infection
- •High blood pressure
- •Low levels of red and white blood cells and platelets (pancytopenia), making you more prone to bleeding, bruising, tiredness, weakness, shortness of breath, and infections
- •Low lymphocyte count (lymphopenia), often due to infection
- •Low magnesium in blood causing tiredness, general weakness, muscle cramps, irritability, and potentially low calcium (hypocalcemia) symptoms like numbness/tingling in hands, feet or lips, muscle cramps, muscle weakness, dizziness, or confusion
- •Low phosphate in blood causing muscle weakness, irritability, or confusion
- •High calcium in blood causing slower reflexes and weak skeletal muscles
- •High potassium in blood causing abnormal heart rhythm
- •Low sodium in blood causing tiredness, confusion, muscle twitching, seizures, or coma
- •High uric acid in blood causing gout (a type of arthritis)
- •Low blood pressure causing dizziness or fainting
- •Sore or dry mouth
- •Taste changes
- •Abdominal swelling
- •Confusion
- •Depression
- •Loss of consciousness, fainting
- •Blurred vision (cataract)
- •Kidney damage
- •Inability to urinate
- •Abnormal liver test results
- •Pelvic pain
- •Weight loss
RARE
- •Stroke
- •Liver inflammation (hepatitis) causing itchy skin, yellow skin/eyes (jaundice), pale stools, dark urine, or stomach pain
- •Tumor lysis syndrome, where cancer cells break down releasing toxic substances, potentially leading to kidney problems
- •Underactive thyroid (hypothyroidism) causing tiredness, sluggishness, muscle weakness, slow heart rate, or weight gain
- •Organ rejection (e.g., heart or liver transplant)
Important Warnings
- Pomalidomide Glenmark is expected to cause severe birth defects and possibly death to an unborn child. Do not take this medicine if you are pregnant, think you might be pregnant, or are planning to become pregnant. Both men and women taking this medicine must use reliable contraception during treatment and for a period after.
- Do not take this medicine if you are allergic to pomalidomide or any other ingredients in this medicine. Tell your doctor if you have had an allergic reaction to similar medicines like thalidomide or lenalidomide.
- Tell your doctor if you have ever had blood clots. This medicine can increase the risk of blood clots.
- Tell your doctor if you have had a heart attack, heart failure, breathing problems, smoke, or have high blood pressure or high cholesterol.
- If you have a lot of cancer cells in your body, they might break down quickly, leading to kidney problems or irregular heartbeats. This is called tumor lysis syndrome.
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- Tell your doctor if you have or have had nerve damage (neuropathy), which causes tingling or pain in your hands or feet.
- Tell your doctor if you have ever had hepatitis B infection. This medicine might make the virus active again.
- Seek urgent medical help if you get a widespread rash, red skin, high fever, flu-like symptoms, swollen lymph nodes, or other organ problems. These can be signs of severe skin reactions.
- It's important to know that patients with multiple myeloma treated with pomalidomide may develop other types of cancer. Your doctor will carefully consider the benefits and risks when prescribing this medicine.
- Tell your doctor or nurse right away if you notice blurred vision, loss of vision, double vision, trouble speaking, weakness in an arm or leg, changes in how you walk, balance problems, constant numbness, loss of sensation, memory loss, or confusion. These could be signs of a serious brain disease called progressive multifocal leukoencephalopathy (PML).
- This medicine can make you feel tired, dizzy, weak, or confused. If this happens, do not drive or use tools or machines.
- Do not donate blood or sperm during treatment and for a period after.
- This medicine is not recommended for children or young people under 18 years old.