Pomalidomid Devatis
Pomalidomid Devatis is a medicine used to treat a type of cancer called multiple myeloma in adults.
Form
kapseli, kova
Strength
2 mg
Active Ingredient
Pomalidomide
Manufacturer
Devatis GmbH
How to Use
Dosage
The recommended starting dose is 4 mg once a day.
Method
Swallow the capsules whole with water. You can take them with or without food. Take your capsules at about the same time each day. Do not break, open, or chew the capsules.
Important
The maximum daily dose for Pomalidomid Devatis is 4 mg.
Possible Side Effects
COMMON
- •Shortness of breath
- •Lung infections (pneumonia, bronchitis)
- •Nose, sinus, and throat infections
- •Flu-like symptoms
- •Low red blood cells (anemia) causing tiredness and weakness
- •Low potassium levels causing weakness, muscle cramps, muscle pain, heart palpitations, tingling, numbness, or breathing problems
- •High blood sugar
- •Fast and irregular heartbeat (atrial fibrillation)
- •Loss of appetite
- •Constipation, diarrhea, or nausea
- •Vomiting
- •Stomach pain
- •Fatigue (tiredness)
- •Difficulty sleeping or waking up
- •Dizziness, trembling
- •Muscle cramps, muscle weakness
- •Bone pain, back pain
- •Numbness, tingling or burning sensation in skin, pain in hands or feet (peripheral sensory neuropathy)
- •Swelling in the body, including arms and legs
- •Rashes
- •Urinary tract infection (burning sensation during urination, frequent urination)
- •Falls
- •Bleeding in the head
- •Reduced movement or sensation in hands, arms, feet, and legs due to nerve damage (peripheral sensorimotor neuropathy)
- •Dizziness (vertigo), which can make standing or normal movement difficult
- •Fluid retention
- •Hives (urticaria)
- •Itching skin
- •Shingles (herpes zoster)
- •Heart attack (chest pain spreading to arms, neck, jaw, sweating, shortness of breath, nausea, vomiting)
- •Chest pain, lung or bronchial infection
- •High blood pressure
- •Low levels of red and white blood cells and platelets (pansytopenia) making you more prone to bleeding, bruising, infections, tiredness, weakness, and shortness of breath
- •Low lymphocyte count (a type of white blood cell), often due to infection
- •Low magnesium levels (hypomagnesemia) causing tiredness, weakness, muscle cramps, irritability, numbness/tingling in hands, feet, or lips, muscle weakness, dizziness, weakness, or confusion
- •Low phosphate levels (hypophosphatemia) causing muscle weakness, irritability, or confusion
- •High calcium levels (hypercalcemia) causing slower reflexes and weakness in skeletal muscles
- •High potassium levels (hyperkalemia) causing abnormal heart rhythm
- •Low sodium levels (hyponatremia) causing tiredness, confusion, muscle twitching, seizures, or coma
- •High uric acid levels (hyperuricemia) causing gout (arthritis)
- •Low blood pressure, causing dizziness or fainting
- •Sore or dry mouth
- •Changes in taste
- •Abdominal swelling
- •Confusion
- •Depression
- •Loss of consciousness, fainting
- •Blurred vision (cataract)
- •Kidney damage
- •Inability to urinate
- •Abnormal liver test results
- •Pelvic pain
- •Weight loss
RARE
- •Stroke
- •Liver inflammation (hepatitis) causing itchy skin, yellow skin/eyes, pale stools, dark urine, and stomach pain
- •Breakdown of cancer cells (tumor lysis syndrome) releasing toxic substances into blood, leading to kidney problems
- •Underactive thyroid gland (hypothyroidism) causing tiredness, sluggishness, muscle weakness, slow heart rate, and weight gain
Important Warnings
- This medicine can cause severe birth defects and may harm an unborn baby. Do not take it if you are pregnant, might become pregnant, or plan to get pregnant. You must use reliable birth control during treatment and for a period after.
- Do not take this medicine if you are allergic to pomalidomide or any similar medicines (like thalidomide or lenalidomide) or any other ingredients in this medicine.
- Tell your doctor if you have ever had blood clots, a heart attack, heart failure, breathing problems, if you smoke, or have high blood pressure or high cholesterol, as this medicine can increase the risk of blood clots.
- Stop taking this medicine and get medical help right away if you develop a severe skin reaction with symptoms like widespread rash, red skin, high fever, flu-like symptoms, swollen lymph nodes, or signs affecting other organs (like DRESS or Stevens-Johnson syndrome).
- Tell your doctor or nurse right away if you experience blurred vision, vision loss, double vision, trouble speaking, weakness in an arm or leg, changes in walking or balance, ongoing numbness, loss of feeling, memory loss, or confusion. These could be signs of a serious and potentially fatal brain condition called PML (progressive multifocal leukoencephalopathy).
Show 3 more warnings
- Tell your doctor if you have ever had Hepatitis B infection, as this medicine can cause the virus to become active again.
- Patients treated with Pomalidomid Devatis for multiple myeloma may develop other types of cancer. Your doctor will carefully consider the benefits and risks of this treatment.
- Do not donate blood or semen during treatment and for 7 days after stopping the medicine.