Pirfenidone ratiopharm
Pirfenidone ratiopharm helps reduce lung scarring and swelling in adults with idiopathic pulmonary fibrosis, making it easier to breathe.
Form
tabletti, kalvopäällysteinen
Strength
801 mg
Active Ingredient
Pirfenidone
Manufacturer
ratiopharm GmbH
How to Use
Dosage
The dose is gradually increased. The maintenance dose is 801 mg (3 yellow tablets or 1 purple tablet) three times a day.
Method
Swallow the tablets whole with water, during or after a meal, to reduce side effects like nausea and dizziness.
Important
The maximum daily dose is 2403 mg.
Possible Side Effects
COMMON
- •Throat or respiratory tract infections that may spread to the lungs and/or sinusitis
- •Nausea
- •Stomach problems like acid reflux, vomiting, constipation, indigestion, abdominal discomfort, bloating, stomach pain, heartburn, and gas
- •Diarrhea
- •Weight loss
- •Decreased appetite
- •Difficulty sleeping
- •Fatigue or feeling tired
- •Dizziness
- •Headache
- •Shortness of breath
- •Cough
- •Joint pain
- •Urinary tract infections
- •Sleepiness
- •Taste changes
- •Hot flashes
- •Skin reactions to sunlight or sunlamps, sunburn
- •Skin problems like itching, redness, dry skin, rash
- •Muscle pain
- •Chest pain
- •Increased liver enzyme levels in blood tests
RARE
- •Low sodium levels in the blood, which can cause headache, dizziness, confusion, weakness, muscle cramps, nausea, and vomiting.
- •Blood tests may show a decreased number of white blood cells.
Important Warnings
- Do not use if you are allergic to pirfenidone or if you have had swelling of the face, lips, or tongue with breathing difficulties when using pirfenidone previously.
- Do not use if you are taking fluvoxamine (used for depression or obsessive-compulsive disorder).
- Do not use if you have severe or advanced liver disease or kidney disease requiring dialysis.
- Avoid sun exposure and use sunscreen and protective clothing during treatment, as this medicine can make you more sensitive to sunlight.
- Stop smoking before and during treatment, as smoking can reduce the medicine's effectiveness.
Show 4 more warnings
- This medicine may cause dizziness and fatigue. Be careful when driving or operating machinery.
- This medicine can cause serious liver problems. You will have regular blood tests to monitor your liver function.
- If you notice severe skin reactions, such as widespread blistering or peeling skin, stop taking the medicine and seek immediate medical attention.
- If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before use. Use during pregnancy should be avoided.