Piperacillin/Tazobactam Stada
This medicine, Piperacillin/Tazobactam Stada, is an antibiotic that combines two drugs to fight many types of bacteria, including those that might otherwise resist antibiotics.
Form
infuusiokuiva-aine, liuosta varten
Strength
4 g / 0.5 g
Active Ingredient
Piperacillin sodium
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
The recommended dose for adults and adolescents (12 years and older) is 4 g/0.5 g of piperacillin/tazobactam, given into a vein every 6-8 hours.
Method
A doctor or nurse will give you this medicine as a slow drip (infusion) into a vein over 30 minutes.
Important
For adults and adolescents, the maximum daily dose is usually 16 g/2 g (given as 4 g/0.5 g up to four times a day). For children, your doctor will calculate the dose based on their weight, and a single dose should not be more than 4 g/0.5 g.
Possible Side Effects
COMMON
- •Diarrhea
- •Fungal infection
- •Changes in blood cell counts or proteins, affecting clotting
- •Headache, sleeplessness
- •Stomach pain, vomiting, nausea, constipation, upset stomach
- •Increased liver enzyme levels
- •Rash, itching
- •Abnormal kidney blood test results
- •Fever, reaction at the injection site
RARE
- •Decreased white blood cells, prolonged blood clotting time
- •Low blood potassium or blood sugar
- •Seizures
- •Low blood pressure, inflamed veins (tenderness or redness in the affected area), skin redness
- •Increased bilirubin in blood
- •Other skin reactions, such as skin changes or hives
- •Joint and muscle pain, chills
- •Severe lack of white blood cells (agranulocytosis), nosebleeds, severe colon inflammation, mouth sores, skin peeling all over the body
- •Severe skin rashes, such as blisters, peeling skin, or red, target-like spots (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- •Severe allergic reaction that can affect the skin and internal organs, like kidneys and liver (DRESS syndrome)
- •Swelling of the face, lips, tongue, or other body parts
- •Shortness of breath, wheezing, or difficulty breathing
- •Yellowing of your skin or the whites of your eyes
- •Damage to blood cells, which may include shortness of breath, bleeding, or bruising
- •Severe or persistent diarrhea with fever and weakness
- •Sudden confusion or disorientation
Important Warnings
- Do not use this medicine if you are allergic to piperacillin, tazobactam, other penicillins, cephalosporins, or similar antibiotics.
- Tell your doctor right away if you have diarrhea before, during, or after treatment. Do not take anti-diarrhea medicine without talking to your doctor first.
- Tell your doctor if you have kidney or liver problems, are on dialysis, or have low potassium levels in your blood. Your doctor may need to check your blood values.
- The risk of kidney problems may increase if you take this medicine at the same time as another antibiotic called vancomycin.
- Tell your doctor if you are taking blood thinners or if you experience any unexpected bleeding during treatment.
Show 3 more warnings
- Tell your doctor if you have seizures during treatment or if you think your infection is getting worse or you have a new infection.
- Seek immediate medical attention if you have several symptoms like fever, swollen glands, weakness, dizziness, shortness of breath, bruising, or rash, as these could be signs of a severe immune condition (hemophagocytic lymphohistiocytosis).
- This medicine is not recommended for children under 2 years old.