Piperacillin/Tazobactam Fresenius Kabi
Piperacillin and tazobactam is an antibiotic used to treat many types of bacterial infections.
Form
infuusiokuiva-aine, liuosta varten
Strength
2 g / 0.25 g
Active Ingredient
Piperacillin sodium
Manufacturer
Fresenius Kabi AB
How to Use
Dosage
The doctor or nurse will determine the correct dose for you or your child. For adults, it's typically 4 g/0.5 g every 6-8 hours. For children (2-12 years), the dose is based on body weight, given every 6 or 8 hours depending on the infection.
Method
This medicine is given as a drip (infusion) into a vein over about 30 minutes.
Important
The maximum daily dose for adults is typically 16 g of piperacillin and 2 g of tazobactam. A single dose for children should not exceed 4 g of piperacillin and 0.5 g of tazobactam.
Possible Side Effects
COMMON
- •Diarrhea
- •Yeast infection
- •Headache, trouble sleeping
- •Stomach pain, nausea, vomiting, constipation, indigestion
- •Rash, itching
- •Fever, reaction at the injection site
- •Changes in blood tests (e.g., liver enzymes, kidney function, or blood cell counts like platelets, red blood cells, or hemoglobin)
RARE
- •Serious changes in blood cells (e.g., severe decrease in white blood cells, red blood cells, or platelets; or increased platelets)
- •Seizures
- •Low blood pressure, inflammation of veins
- •Red skin reactions, skin changes, hives
- •Joint and muscle pain, chills
- •Nosebleeds
- •Severe inflammation of the colon, mouth sores
- •Skin peeling over the whole body
- •Liver inflammation, yellowing of the skin or eyes
- •Kidney problems or poor kidney function
- •Lung disease (with increased eosinophils)
- •Confusion or delirium
- •Swelling of the face, lips, tongue, or other body parts
- •Shortness of breath, wheezing, or breathing difficulties
Important Warnings
- Do not use if you are allergic to piperacillin, tazobactam, any other ingredients in this medicine, or to other penicillin-type antibiotics like cephalosporins or other beta-lactamase inhibitors.
- Seek immediate medical help if you develop severe skin reactions, such as widespread rash, blisters, or skin peeling (like Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS, or AGEP).
- Tell your doctor if you have severe or persistent diarrhea during or after treatment.
- Inform your doctor if you have low potassium levels in your blood.
- Tell your doctor if you have kidney or liver problems or are on dialysis.
Show 5 more warnings
- Tell your doctor if you are taking blood-thinning medicines (anticoagulants) or experience unexpected bleeding.
- Taking this medicine with vancomycin can increase the risk of kidney problems.
- Tell your doctor if you experience seizures during treatment.
- Seek medical attention immediately if you have symptoms like fever, swollen glands, weakness, dizziness, shortness of breath, bruising, or rash, as these could be signs of a serious immune condition (HLH).
- This medicine is not recommended for children under 2 years old.