Perindopril Orion
Perindopril Orion helps widen blood vessels, making it easier for your heart to pump blood, and is used to treat high blood pressure, heart failure, and to reduce the risk of heart problems.
How to Use
Dosage
The usual starting dose is 2 mg or 4 mg once a day, depending on your condition and age. Your doctor will adjust the dose for you.
Method
Swallow the tablet whole with a glass of water, preferably at the same time each day, in the morning before breakfast.
The maximum daily dose is 8 mg for high blood pressure and stable coronary artery disease, and 4 mg for heart failure.
Possible Side Effects
- •Headache
- •Dizziness
- •Tingling sensation in your skin
- •Vision problems
- •Ringing or buzzing in your ears (tinnitus)
- •Cough
- •Shortness of breath
- •Stomach problems (like nausea, vomiting, diarrhea, indigestion, or constipation)
- •Skin rash or itching
- •Muscle cramps
- •Feeling weak
- •Low blood pressure
- •Mood changes
- •Sleep problems
- •Dry mouth
- •Severe skin reactions or blistering skin
- •Kidney problems
- •Impotence
- •Increased sweating
- •Fainting or drowsiness
- •Fast heartbeat or palpitations
- •Joint pain, muscle pain, or chest pain
- •Feeling generally unwell or fever
- •Changes in blood tests (e.g., potassium, blood sugar)
- •Depression or confusion
- •Reduced or no urine production
- •Cold, numb fingers or toes (Raynaud's phenomenon)
Important Warnings
- Do not take if you are allergic to perindopril or any other ACE inhibitor, or if you have had swelling of the face, tongue, or throat (angioedema).
- Do not take if you are more than 3 months pregnant, or if you plan to become pregnant.
- Do not take if you have diabetes or kidney problems and are taking a blood pressure-lowering medicine called aliskiren.
- Do not take if you are taking a combination medicine containing sacubitril and valsartan for chronic heart failure, as it increases the risk of angioedema.
- This medicine is not recommended for children and adolescents under 18 years of age.
Show 2 more warnings
- This medicine may cause dizziness or tiredness, so do not drive or use machines if you feel this way.
- Do not stop taking this medicine without talking to your doctor first.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Reduce the dose in moderately severe renal impairment. Monitor renal function and potassium concentrations during the pharmacotherapy. Avoid concurrent use of NSAIDs. (updated 14.4.2025)