Pentiro
Pentiro contains three medicines in one tablet and is used to treat Parkinson's disease.
Form
tabletti, kalvopäällysteinen
Strength
175 mg / 43.75 mg / 200 mg
Active Ingredient
Levodopa
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
Your doctor will tell you how many Pentiro tablets to take each day.
Method
Do not divide or break the tablet. Always take only one Pentiro tablet at a time.
Important
Do not take more than 10 tablets per day for 50mg, 100mg, or 150mg strengths. Do not take more than 8 tablets per day for 175mg strength. Do not take more than 7 tablets per day for 200mg strength.
Possible Side Effects
COMMON
- •Involuntary movements
- •Feeling sick (nausea)
- •Harmless reddish-brown urine
- •Muscle pain
- •Diarrhea
- •Urinary tract infection
- •Dizziness or fainting due to low blood pressure
- •High blood pressure
- •Worsening of Parkinson's disease symptoms
- •Dizziness, sleepiness
- •Vomiting, stomach pain and discomfort, heartburn, dry mouth, constipation
- •Trouble sleeping, seeing or hearing things that are not there (hallucinations), confusion, bad dreams (including nightmares), tiredness
- •Mood changes, including memory problems, anxiety, and depression (possibly with thoughts of harming yourself)
- •Heart problems (like chest pain), irregular heart rate or rhythm
- •Increased tendency to fall
- •Shortness of breath
- •Increased sweating, skin rash
- •Muscle cramps, swollen legs
- •Blurred vision
- •Anemia (low red blood cells)
- •Loss of appetite, weight loss
- •Headache, joint pain
RARE
- •Heart attack
- •Bleeding in the stomach or intestines
- •Changes in blood cells (may lead to bleeding), abnormal liver test results
- •Seizures
- •Agitation
- •Psychotic symptoms (like delusions or hallucinations)
- •Colitis (inflammation of the large intestine)
- •Discoloration of skin, nails, hair, or sweat (not urine)
- •Difficulty swallowing
- •Inability to urinate
- •Hepatitis (liver inflammation)
- •Itching
- •Craving higher doses of Pentiro than needed, leading to unusual movements, mood swings, or other side effects (dopamine dysregulation syndrome).
- •Strong urges to do harmful things you can't control, such as compulsive gambling, overeating, uncontrolled spending, or unusually strong sexual urges and thoughts.
Important Warnings
- Do not take Pentiro if you are allergic to levodopa, carbidopa, entacapone, soy, peanuts, or any other ingredients in this medicine.
- If you have narrow-angle glaucoma (an eye disease).
- If you have a tumor on your adrenal gland.
- If you are taking certain types of antidepressants (MAO inhibitors).
- If you have had neuroleptic malignant syndrome (a rare severe reaction to medicines) or rhabdomyolysis (a rare muscle disease).
Show 10 more warnings
- If you have severe liver disease.
- Contact your doctor right away if you have very stiff or twitching muscles, shaking, restlessness, confusion, fever, fast heart rate, or big changes in blood pressure. These could be signs of serious reactions like neuroleptic malignant syndrome or rhabdomyolysis.
- Get medical help right away if you have signs of an allergic reaction, such as hives, itching, rash, swelling of your face, lips, tongue, or throat, which can make it hard to breathe or swallow.
- Pentiro is not for children or teenagers under 18 years old.
- Pentiro can lower your blood pressure, making you feel dizzy or light-headed. Be very careful when driving or using machines.
- If you feel very sleepy or suddenly fall asleep, wait until you are fully awake before driving or doing anything that needs your full attention. Otherwise, you could hurt yourself or others.
- Pentiro can make it harder for your body to absorb iron. Do not take Pentiro and iron supplements at the same time. Wait at least 2-3 hours between taking them.
- Pentiro can be taken with or without food. Sometimes, high-protein foods (like meat, fish, dairy) can make Pentiro less absorbed. Ask your doctor if this might affect you.
- If you are pregnant, breastfeeding, think you might be pregnant, or are planning a baby, ask your doctor for advice before taking this medicine. Do not breastfeed while taking Pentiro.
- Do not stop taking Pentiro unless your doctor tells you to. Your doctor might need to change the doses of your other Parkinson's medicines to keep your symptoms controlled. Suddenly stopping can cause side effects.