Pazopanib STADA
This medicine stops cancer cells from growing and spreading by blocking certain proteins in the body, and it's used to treat kidney cancer and a type of soft tissue cancer.
Form
tabletti, kalvopäällysteinen
Strength
400 mg
Active Ingredient
Pazopanib hydrochloride
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
Your doctor will tell you your dose, but it's usually 800 mg (e.g., four 200 mg tablets or two 400 mg tablets) once daily.
Method
Take the medicine on an empty stomach, at least 2 hours after a meal or 1 hour before a meal. Swallow the tablets whole with water; do not chew or crush them.
Important
The maximum daily dose is 800 mg.
Possible Side Effects
COMMON
- •High blood pressure
- •Diarrhea
- •Nausea, vomiting
- •Stomach pain
- •Loss of appetite
- •Weight loss
- •Changes in taste or loss of taste
- •Headache
- •Tiredness, weakness
- •Hair color changes, hair loss or thinning
- •Rash, loss of skin color, redness, itching
- •Swelling in hands or feet
- •Nosebleeds
- •Dry mouth or mouth sores
- •Infections
- •Trouble sleeping
- •Dizziness
- •Blurred vision
- •Muscle and joint pain
- •Cough, shortness of breath
- •Underactive thyroid
- •Abnormal liver function
RARE
- •Stroke
- •Heart attack
- •Blood clot in lungs (pulmonary embolism)
- •Severe bleeding (e.g., in digestive system, kidneys, brain)
- •Hole in the bowel (perforation) or abnormal connection (fistula)
- •Sudden, severe high blood pressure (hypertensive crisis)
- •Inflammation of the pancreas (pancreatitis)
- •Yellow skin and eyes (jaundice)
- •Lung inflammation (pneumonitis)
- •Blood vessel problems like bulging or tearing (aneurysm or arterial dissection)
- •Tumor lysis syndrome (rapid breakdown of cancer cells)
- •Severe liver failure
Important Warnings
- Do not take if you are allergic to pazopanib or any other ingredients in this medicine.
- Tell your doctor if you have had heart or liver problems, or if you have high blood pressure.
- Inform your doctor if you have had bleeding, blood clots, or blood vessel issues.
- Tell your doctor if you have had stomach or bowel problems, like a hole (perforation) or an abnormal connection (fistula).
- If you are having surgery, tell your doctor; you will need to stop this medicine at least 7 days before.
Show 3 more warnings
- Do not use if you are pregnant, planning to get pregnant, or breastfeeding. Use reliable contraception during treatment and for 2 weeks after.
- Avoid driving or using machines if this medicine makes you feel weak, tired, or dizzy.
- Do not drink grapefruit juice, as it can increase the risk of side effects.