Parkadin
Parkadin helps treat Parkinson's disease by improving muscle control, reducing stiffness and tremors, and improving mobility.
Form
kapseli, kova
Strength
100 mg
Active Ingredient
Amantadine hydrochloride
Manufacturer
Renata Pharmaceuticals (Ireland) Limited
How to Use
Dosage
Initially one 100 mg capsule daily; after one week, your doctor may increase the dose to two 100 mg capsules per day (one capsule twice daily).
Method
Swallow the capsules whole with water after a meal, preferably in the morning. If taking two doses per day, the second dose should be taken in the afternoon after a meal.
Important
The maximum daily maintenance dose is 100 mg (one capsule) for elderly patients without kidney impairment.
Possible Side Effects
COMMON
- •Fluid retention in legs
- •Impaired attention
- •Bluish or reddish net-like discoloration of the skin, especially on arms and legs (livedo reticularis)
RARE
- •Hallucinations (seeing or hearing things that are not there)
- •Depression (feeling sad)
- •Anxiety
- •Speech difficulties (stuttering)
- •Coordination problems (difficulty moving the body precisely)
- •Severe confusion or disorientation
- •Severe psychosis (mental illness affecting behavior)
- •Uncontrolled movements (dyskinesia)
- •Seizures
- •Corneal changes (damage to the front of the eye), fluid retention in the cornea, decreased vision
- •Rash
- •Urinary retention (difficulty emptying the bladder)
- •Urinary incontinence (inability to control urination)
- •Neuroleptic Malignant Syndrome (a serious condition with rigid muscles, high fever, profuse sweating, reduced consciousness)
- •Heart failure
- •Increased susceptibility to infections due to reduced white blood cells (leukopenia), with symptoms like fever, sore throat, mouth sores
- •Restlessness (agitation)
- •Nervousness
- •Elevated mood (euphoria)
- •Dizziness
- •Lightheadedness (brief loss of consciousness)
- •Headache
- •Insomnia
- •Nightmares
- •Drowsiness (lethargy)
- •Blurred vision
- •Palpitations (irregular heartbeat)
- •Drop in blood pressure when standing up (orthostatic hypotension), sometimes with dizziness
- •Dry mouth
- •Decreased appetite
- •Excessive sweating
- •Nausea
- •Vomiting
- •Constipation (bowel obstruction)
- •Tremor (shaking)
- •Diarrhea
- •Increased liver enzymes (in blood tests)
- •Photosensitivity (skin reacts strongly to sun)
Important Warnings
- Do not take if you are allergic to amantadine hydrochloride or any other ingredient in this medicine.
- Do not take if you have epilepsy that is not properly treated.
- Do not take if you have a severe mental illness (psychosis) where your behavior and actions are impaired.
- Talk to your doctor if you have epilepsy.
- Talk to your doctor if you have had thoughts of suicide or self-harm.
Show 15 more warnings
- Talk to your doctor if you have liver or kidney disease.
- Talk to your doctor if you have a history of heart and vascular disease.
- Talk to your doctor if you currently have heart problems or heart failure.
- Talk to your doctor if you have or have had stomach ulcers.
- Talk to your doctor if you have or have had recurrent skin problems (eczema).
- Talk to your doctor if you have low blood pressure.
- Talk to your doctor if you have mental health problems, such as schizophrenia or dementia.
- Talk to your doctor if you have certain hormonal disorders.
- Talk to your doctor if you have untreated glaucoma (high eye pressure).
- Tell your doctor if you or your family notice you developing unusual urges, like a strong urge to gamble or an increased sex drive.
- Contact an eye doctor immediately if you experience blurred vision or other eye problems.
- Do not stop taking this medicine suddenly; always talk to your doctor first.
- Do not drink alcohol while taking this medicine.
- Do not breastfeed while taking this medicine.
- Do not drive or use machines if the medicine makes you dizzy, blurs your vision, or causes confusion.