Pamorelin
Pamorelin 22.5 mg is a long-acting medicine that lowers sex hormone levels to treat advanced prostate cancer in men and early puberty in children.
Form
injektiokuiva-aine ja liuotin, depotsuspensiota varten
Strength
22.5 mg
Active Ingredient
Triptorelin embonate
Manufacturer
Institut Produits Synthese (IPSEN) AB
How to Use
Dosage
One vial of Pamorelin 22.5 mg
Method
Given as an injection into a muscle every six months (24 weeks).
Important
One dose (one vial) every six months. Do not take more often than prescribed.
Possible Side Effects
COMMON
- •Hot flushes
- •Feeling weak
- •More sweating
- •Back pain
- •Tingling in legs (for men)
- •Less sex drive (for men)
- •Trouble getting or keeping an erection (for men)
- •Feeling sick (nausea)
- •Dry mouth
- •Pain, bruising, redness, or swelling where the injection was given
- •Muscle and bone pain, arm and leg pain
- •Swelling due to fluid in the body
- •Lower stomach pain
- •High blood pressure
- •Allergic reaction
- •Weight gain
- •Feeling dizzy
- •Headache
- •Mood changes or feeling sad (depression)
- •Vaginal bleeding (for girls in the first month of treatment for early puberty)
- •Acne
RARE
- •Severe allergic reaction causing trouble swallowing or breathing, or swelling of lips, face, throat, or tongue
- •Seizures (fits)
- •Blurred vision or other eye problems
- •Ringing in the ears or feeling like things are spinning (vertigo)
- •Constipation
- •Diarrhea
- •Vomiting
- •Drowsiness or feeling sleepy
- •Shaking, sweating, fever, and pain (flu-like symptoms)
- •Changes in blood tests (like liver values)
- •Weight loss
- •Loss of appetite or increased appetite
- •Gout (severe joint pain, usually in the big toe)
- •Diabetes or high blood fat levels
- •Muscle cramps, weakness, or tenderness
- •Bone pain
- •Numbness or tingling feeling
- •Trouble sleeping or feeling irritable
- •Breast enlargement or pain (for men)
- •Smaller testicles or testicle pain (for men)
- •Trouble breathing
- •Hair loss
- •Itching, rash, or red skin
- •Hives (itchy red bumps on skin)
- •Waking up at night to pee or trouble peeing
- •Nosebleeds
- •Red or purple spots on the skin
- •Bloated feeling in the stomach or gas
- •Changes in taste
- •Chest pain
- •Trouble standing
- •Inflammation of the nose or throat
- •Increased body temperature
- •Stiff or swollen joints, or stiff muscles and bones (osteoarthritis)
- •Memory loss
- •Confusion, less activity, or feeling too happy (elevated mood)
- •Shortness of breath when lying down
- •Blisters
- •Low blood pressure
- •Changes in heart rhythm seen on an ECG test
- •General feeling of being unwell
- •Anxiety
- •Loss of bladder control (incontinence)
- •Increased risk of bleeding in the pituitary gland (if you have a pituitary tumor)
- •Anemia (low red blood cell count)
- •Neck pain
- •Too much pressure in the brain, causing headache, double vision, other sight problems, and ringing in the ears
Important Warnings
- Do not use if you are allergic to triptorelin, GnRH, other similar medicines, or any other ingredients.
- Do not use if you are pregnant or breastfeeding.
- Tell your doctor if you feel depressed, as this medicine can cause severe depression.
- If you take blood thinners, the injection might cause bruising.
- Tell your doctor immediately if you have seizures (fits), even if you haven't had them before.
Show 10 more warnings
- This medicine can weaken bones in adults. Tell your doctor if you or your family have weak bones, if you drink or smoke a lot, have a poor diet, or take medicines like epilepsy drugs or steroids.
- If you have heart problems or take medicine for them, as this medicine can increase the risk of heart rhythm issues.
- Tell your doctor if you have diabetes or other heart or blood vessel problems.
- For men, cancer symptoms might temporarily worsen at the start of treatment. Contact your doctor if this happens.
- Seek immediate medical help if you experience leg pain, numbness, weakness, or trouble urinating in the first weeks of treatment.
- If you have a pituitary gland tumor you don't know about, Pamorelin might reveal it, causing sudden headaches, vomiting, vision problems, or eye muscle paralysis.
- For children, tell your doctor if you have a growing brain tumor, as it might affect your treatment.
- Girls being treated for early puberty might have vaginal bleeding in the first month.
- For children, contact your doctor immediately if you have severe or repeated headaches, vision problems, or ringing in your ears.
- After treatment stops, children might develop hip problems like stiffness, limping, or pain in the groin or thigh. Talk to your doctor if this happens.