Palonosetron Reig Jofre
This medicine is used to prevent nausea and vomiting caused by cancer treatments by blocking a body chemical called serotonin.
Form
injektioneste, liuos
Strength
250 mikrog
Active Ingredient
Palonosetron hydrochloride
Manufacturer
Laboratorio Reig Jofré S.A.
How to Use
Dosage
Adults usually receive 250 micrograms. For children and adolescents, the dose is based on their body weight.
Method
The medicine is given as an injection into a vein about 30 minutes before chemotherapy. For children and adolescents, it's a slow drip into a vein.
Important
The maximum daily dose for adults is 250 micrograms, and for children and adolescents, it is 1500 micrograms.
Possible Side Effects
COMMON
- •Headache
- •Dizziness
- •Constipation
- •Diarrhoea
RARE
- •Changes in vein color and widening
- •Unusual good mood or anxiety
- •Drowsiness or difficulty sleeping
- •Reduced appetite or lack of appetite
- •Weakness, tiredness, flu-like symptoms
- •Numbness, burning, stinging, or itching sensation on the skin
- •Itchy rash or hives
- •Blurred vision or eye irritation
- •Motion sickness
- •Ringing in the ears
- •Hiccups, flatulence, dry mouth, or indigestion
- •Stomach pain
- •Difficulty urinating
- •Joint pain
- •High or low blood pressure
- •Abnormal heart rate or reduced blood flow to the heart
- •Abnormal potassium levels in the blood
- •High blood sugar levels or sugar in urine
- •Low calcium levels in the blood
- •High bilirubin levels in the blood
- •High liver enzyme levels
- •Abnormalities in heart tracing (ECG), such as a prolonged QT interval
- •Burning sensation, pain, or redness at the injection/infusion site
- •Involuntary movements
- •Cough or shortness of breath
- •Nosebleed
Important Warnings
- Do not use this medicine if you are allergic to palonosetron or any other ingredient.
- Tell your doctor if you have had a bowel blockage or frequent constipation.
- Tell your doctor if you or your family have had heart problems, such as an irregular heartbeat.
- Tell your doctor if your blood salt levels (like potassium or magnesium) are unusual and have not been treated.
- Tell your doctor if you are taking other medicines, especially for depression or anxiety (SSRI, SNRI) or medicines that affect your heart rhythm.
Show 3 more warnings
- If you are pregnant or think you might be, your doctor will only give you this medicine if it is absolutely necessary.
- Talk to your doctor if you are breastfeeding, as it is not known if the medicine passes into breast milk.
- This medicine may cause dizziness or tiredness. Do not drive or operate machinery if you feel these effects.