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Palmeux

Palmeux is a medicine used for the long-term treatment of schizophrenia symptoms in adults who have been stabilized with similar medications.

Form
Injektioneste, depotsuspensio, esitäytetty ruisku
Strength
150 mg
Active Ingredient
Paliperidone palmitate
Manufacturer
Amdipharm Limited

How to Use

Dosage

The first dose is 150 mg and the second is 100 mg, given one week apart in the upper arm. After that, 25-150 mg is given monthly in the upper arm or buttock.

Method

This medicine is given as an injection by a doctor or nurse into your upper arm or buttock.

Important

The maximum dose given at one time is 150 mg. Your doctor will adjust your monthly dose based on your symptoms.

Possible Side Effects

COMMON
  • •Difficulty falling asleep or interrupted sleep.
  • •Flu-like symptoms, urinary tract infection, feeling unwell.
  • •Increased levels of the hormone prolactin in your blood (may cause breast swelling in men, sexual problems, or missed periods/milk discharge in women).
  • •High blood sugar, weight gain, weight loss, decreased appetite.
  • •Irritability, depression, anxiety.
  • •Parkinson-like symptoms (slow movements, muscle stiffness, tremors, drooling, lack of facial expression, slow shuffling walk).
  • •Restlessness, drowsiness or feeling less alert.
  • •Dystonia (slow or prolonged muscle spasms, often affecting face, eyes, mouth, tongue, or jaw, causing unusual postures).
  • •Dizziness.
  • •Dyskinesia (uncontrolled, jerky, or twitching muscle movements).
  • •Tremor (shaking).
  • •Headache.
  • •Fast heartbeat.
  • •High blood pressure.
  • •Cough, stuffy nose.
  • •Abdominal pain, vomiting, nausea, constipation, diarrhea, indigestion, toothache.
  • •Increased liver enzymes in blood.
  • •Bone or muscle pain, back pain, joint pain.
  • •Missed periods.
  • •Milk discharge from breasts.
  • •Fever, weakness, tiredness.
  • •Injection site reactions (itching, pain, swelling).
RARE
  • •Pneumonia, bronchitis, respiratory tract infection, sinus infection, bladder infection, ear infection, nail fungus infection, tonsillitis, skin infection.
  • •Decreased white blood cells (some types), decreased platelets, anemia.
  • •Allergic reaction.
  • •New or worsened diabetes, increased insulin levels.
  • •Increased appetite.
  • •Loss of appetite, malnutrition, weight loss.
  • •High blood triglycerides and cholesterol.
  • •Sleep disorders, elevated mood (mania), decreased sex drive, nervousness, nightmares.
  • •Tardive dyskinesia (uncontrolled, jerky movements of face, tongue, or other body parts).
  • •Fainting, strong urge to move body parts, dizziness when standing up, difficulty concentrating, speech problems, loss or change of taste, reduced sensation of pain or touch, tingling, prickling, or numbness of the skin.
  • •Blurred vision, eye infection or redness, dry eyes.
  • •Spinning sensation (vertigo), ringing in ears, ear pain.
  • •Abnormal heart rhythm or electrical activity (ECG), including fast heart rate when standing, slow heart rate, fluttering or pounding in the chest.
  • •Low blood pressure, including when standing up quickly (causing weakness, dizziness, or fainting).
  • •Shortness of breath, congested airways, wheezing, sore throat, nosebleed.
  • •Abdominal discomfort, stomach or intestinal infection, difficulty swallowing, dry mouth, excessive gas.
  • •Increased liver enzyme levels (gamma-GT, other liver enzymes).
  • •Hives, itching, rash, hair loss, eczema, dry skin, skin redness, acne.
  • •Increased creatine phosphokinase (CPK) in blood (an enzyme from muscle breakdown).
  • •Muscle cramps, stiff joints, muscle weakness, neck pain.
  • •Urinary incontinence, frequent urination, painful urination.
  • •Erectile dysfunction, ejaculation disorders, missed periods or other menstrual cycle problems (in women), breast development in men, sexual dysfunction, breast pain.
  • •Swelling of face, mouth, eyes, or lips; swelling of body, arms, or legs.
  • •Increased body temperature.
  • •Changes in gait.
  • •Chest pain, chest discomfort, feeling unwell.
  • •Hardening of skin.
  • •Falls.
  • •Skin inflammation caused by mites, abscess under the skin.
  • •Inappropriate secretion of ADH (hormone regulating urine volume).
  • •Life-threatening complications of uncontrolled diabetes.
  • •Low blood sugar.
  • •Excessive water drinking.
  • •Immobility and unresponsiveness while awake (catatonia).
  • •Confusion.
  • •Sleepwalking.
  • •Lack of feelings/emotions.
  • •Inability to have an orgasm.
  • •Neuroleptic Malignant Syndrome (confusion, decreased or loss of consciousness, high fever, severe muscle stiffness).
  • •Brain blood vessel problems, including stroke or mini-stroke.
  • •Seizures.
  • •Balance disorders.
  • •Abnormal coordination.
  • •Glaucoma (increased pressure in the eye).
  • •Eye movement problems, rolling eyes, sensitivity to light, increased tear production, red eyes.
  • •Atrial fibrillation (irregular heartbeat), irregular heartbeat.
  • •Flushing of face and neck (feeling of warmth and redness).
  • •Breathing difficulties during sleep (sleep apnea).
  • •Lung congestion (blood engorgement).
  • •Crackling breathing sounds.
  • •Pancreatitis, swollen tongue, fecal incontinence, very hard stools.
  • •Chapped lips.
  • •Drug rash, skin thickening, dandruff.
  • •Muscle fiber breakdown and muscle pain (rhabdomyolysis).
  • •Joint swelling.
  • •Urinary retention (inability to urinate).
  • •Breast discomfort, breast gland enlargement, breast enlargement.
  • •Vaginal discharge.
  • •Very low body temperature, chills, thirst.
  • •Drug withdrawal syndrome.
  • •Abscess at injection site, deep skin infection, cyst at injection site, bruise at injection site.
  • •Dangerously excessive water intake.
  • •Sleep-related eating disorder.
  • •Coma due to uncontrolled diabetes.
  • •Head shaking.
  • •Reduced oxygen flow to parts of the body.
  • •Rapid, shallow breathing.
  • •Pneumonia caused by inhaling food.
  • •Voice disorders.
  • •Bowel obstruction, paralyzed bowel.
  • •Yellowing of skin and eyes (jaundice).
  • •Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) with blisters and peeling skin, starting in the mouth, nose, eyes, and genitals.
  • •Skin discoloration, flaky itchy scalp or skin.
  • •Abnormal postures.
  • •For babies born to mothers who used this medicine during pregnancy: irritability, slow or prolonged muscle contractions, shaking, drowsiness, breathing problems, or difficulty feeding.
  • •Decreased body temperature.

Important Warnings

  • This medicine has not been studied in elderly patients with dementia. Similar medicines have shown an increased risk of stroke or death in these patients.
  • Do not use this medicine if you are allergic to paliperidone, risperidone, or any other ingredients in Palmeux.
  • Seek immediate medical help if you develop blood clots, especially in your legs (swelling, pain, redness) or lungs (chest pain, breathing difficulties).
  • If you have dementia and experience sudden changes in your mental state, or sudden weakness/numbness on one side of your face, arm, or leg, or slurred speech, seek medical attention as these can be signs of a stroke.
  • Seek immediate medical help if you have fever, muscle stiffness, sweating, or decreased consciousness, as these could be signs of Neuroleptic Malignant Syndrome.
Show 5 more warnings
  • Men, if you experience a prolonged or painful erection, seek immediate medical help (priapism).
  • Inform your doctor if you experience uncontrolled movements of your tongue, mouth, or face, as your treatment might need to be stopped.
  • Seek immediate medical help if you have a severe allergic reaction with fever, swelling of your mouth, face, lips, or tongue, shortness of breath, itching, rash, and sometimes low blood pressure.
  • If you are planning eye surgery, tell your eye doctor that you are taking this medicine, as it can affect your iris during cataract surgery.
  • Tell your doctor if you know you have a dangerously low number of certain white blood cells needed to fight infections.

Additional Information

ATC Code: N05AX13
→ View Professional Information (PDF)→ View Patient Leaflet (PDF)