Oxycorion Depot
Oxycorion Depot is a strong opioid pain reliever used to treat severe pain in adults and adolescents aged 12-18 when other pain medicines are not enough.
Form
depottabletti
Strength
60 mg
Active Ingredient
Oxycodone hydrochloride
Manufacturer
Orion Corporation
How to Use
Dosage
The usual starting dose for adults and adolescents (12-18 years) is 10 mg of oxycodone hydrochloride every 12 hours. For non-cancer pain, a daily dose of 40 mg is often enough, but higher doses may be needed. For cancer pain, doses are usually 80-120 mg daily, and can be increased to 400 mg in some cases.
Method
Swallow the whole tablet with half a glass of water, either with or without food. Take your dose in the morning and evening at the same time each day (e.g., 8 AM and 8 PM). Do not chew, break, or crush the tablets, as this can release too much medicine at once and be dangerous.
Important
For non-cancer pain, typically up to 40 mg daily. For cancer pain, doses can go up to 400 mg daily in specific cases, as directed by your doctor.
Possible Side Effects
COMMON
- •Drowsiness, dizziness, headache
- •Constipation, nausea, vomiting
- •Itching
- •Loss of appetite, decreased appetite
- •Mood changes (e.g., anxiety, depression), changes in activity (feeling calm or sometimes restless and sleepless), and changes in performance (trouble thinking, confusion, speech problems)
- •Severe drowsiness (letargy), trembling (tremor)
- •Breathing difficulties, shortness of breath, or wheezing (bronchospasm)
- •Dry mouth (sometimes with thirst and difficulty swallowing), stomach problems (like pain, diarrhea, indigestion)
- •Skin problems like rash, excessive sweating, sometimes sensitivity to light, itchy rash (hives), or flaky skin
- •Urinary problems (frequent urge to urinate)
- •Weakness (asthenia), tiredness
RARE
- •Allergic reactions (hypersensitivity)
- •Unusual or increased production of a hormone that reduces urine output
- •Dehydration (lack of water in the body)
- •Changes in perception, like feeling unreal or detached (depersonalization), hallucinations (seeing or hearing things that aren't there), mood changes, abnormal sensitivity to sound (hyperacusis), feeling overly happy (euphoria), sadness, restlessness
- •Increased or decreased muscle tone, involuntary muscle contractions, memory loss (amnesia), seizures, high blood pressure, speech problems, reduced sense of touch (hypoesthesia), coordination problems, fainting, tingling or prickling skin (paresthesia), taste disorders
- •Tear production problems, vision problems, constricted pupils
- •Dizziness (vertigo), ringing in the ears (tinnitus)
- •Fast or irregular heartbeat (supraventricular tachycardia, palpitations [with withdrawal symptoms]), widened blood vessels
- •Increased coughing, sore throat (pharyngitis), runny nose, voice changes
- •Mouth ulcers, gum inflammation, mouth inflammation (stomatiitis), difficulty swallowing (dysphagia), gas, belching, bowel blockage (ileus)
- •Increased liver enzymes, urethra spasm
- •Dry skin
- •Urinary retention (difficulty emptying bladder)
- •Sexual dysfunction (decreased sexual desire and impotence), low hormone production in testicles/ovaries (hypogonadism)
- •Accidental injuries, pain (e.g., chest pain), feeling unwell, fluid buildup in tissues (edema), swelling of hands and feet due to fluid buildup, migraine, physical dependence with withdrawal symptoms, tolerance to the medicine, thirst, chills
- •Lymph node disease (lymphadenopathy)
- •Seizures, especially in patients with epilepsy or prone to seizures, muscle spasms (involuntary muscle contractions)
- •Low blood pressure, tendency to faint when standing up
- •Bleeding gums, increased appetite, black stool, tooth discoloration and damage
- •Herpes simplex (skin and mucous membrane disorder), hives (urticaria)
- •Weight changes (increase or decrease), bacterial infection of the tissue under the skin (cellulitis)
- •Anaphylactic or anaphylactoid reaction (severe allergic reaction)
- •Aggression
- •Increased pain sensitivity (hyperalgesia)
- •Tooth decay (caries), dental problems
- •Bile duct obstruction, gallstone attack
- •Absence of menstruation (amenorrhea)
- •Withdrawal symptoms in newborns (irritability, hyperactivity, abnormal sleep patterns, high-pitched crying, trembling, vomiting, diarrhea, poor weight gain) if used long-term during pregnancy
- •Sleep apnea (breathing pauses during sleep)
- •Problem affecting a sphincter muscle in the intestines that can cause severe upper abdominal pain (Oddi's sphincter dysfunction)
Important Warnings
- Do not take if you are allergic to oxycodone hydrochloride or any other ingredient in this medicine.
- Do not take if you have severe breathing problems, like very slow or shallow breathing, or a severe lung disease (such as COPD or severe asthma).
- Do not take if you have certain types of bowel blockage (paralytic ileus), severe stomach pain, or very slow digestion.
- Do not drink alcohol while taking this medicine, as it can cause serious side effects like severe drowsiness, slow breathing, or coma.
- Avoid grapefruit juice, as it can increase the effect of the medicine.
Show 4 more warnings
- Do not take this medicine during pregnancy unless absolutely necessary, as it can harm the baby.
- Do not take this medicine while breastfeeding, as it passes into breast milk and can cause breathing problems for the baby.
- This medicine can make you less alert and slow your reactions, so be careful when driving or using machines.
- If you are elderly, frail, or have kidney or liver problems, your doctor may start you on a lower dose.