Oxycontin Depot
OxyContin Depot is a strong pain medication belonging to a group of medicines called opioids. It is used to relieve severe pain in adults and adolescents over 12 years old when other pain medications are not enough.
How to Use
Dosage
The usual starting dose is 10-20 mg twice a day, every 12 hours. Your doctor may sometimes start you on a 5 mg dose to reduce side effects.
Method
Swallow the tablets whole with enough water. Do not chew, crush, or break the tablets, as this can be dangerous. Take the medicine regularly, for example at 8 AM and 8 PM.
Do not take more medicine than your doctor has prescribed. Also, do not take a double dose to make up for a forgotten one.
Possible Side Effects
- •Dizziness
- •Headache
- •Drowsiness or feeling very sleepy
- •Constipation
- •Vomiting
- •Nausea
- •Itching
- •Loss of appetite
- •Mood and personality changes (e.g., anxiety, feeling down, nervousness, trouble sleeping, confused thoughts)
- •Tremor
- •Shortness of breath
- •Stomach pain or digestive problems
- •Diarrhea
- •Dry mouth
- •Rash
- •Heavy sweating
- •Unusual weakness or tiredness
- •Allergic reactions (e.g., hives, severe allergic reaction)
- •Dehydration
- •Agitation
- •Hallucinations
- •Feeling overly happy (euphoria)
- •Memory loss
- •Seizures
- •Numbness, tingling, or reduced sensitivity to pain or touch
- •Speech difficulties
- •Fainting
- •Changes in taste
- •Vision problems
- •Low blood pressure, especially when standing up
- •Fast heartbeat
- •Breathing difficulties or shallow breathing
- •Bowel problems (e.g., gas, difficulty swallowing, bowel obstruction, severe stomach pain due to a bowel muscle problem)
- •Increased liver enzyme levels
- •Dry skin
- •Difficulty urinating
- •Erection problems or low sex hormones
- •Swelling of hands, ankles, or feet
- •Withdrawal symptoms (such as thirst, chills, muscle aches, needing higher doses, feeling unwell)
- •Aggression
- •Increased sensitivity to pain
- •Sleep apnea (pauses in breathing during sleep)
- •Tooth decay
- •Absent periods in women
- •Withdrawal symptoms in newborns
Important Warnings
- Do not use if you are allergic to oxycodone or any other ingredients in the medicine.
- Avoid use if you have severe breathing difficulties, severe asthma, or heart problems due to chronic lung disease.
- Do not use if your bowel movements are paralyzed or significantly weakened.
- Children under 12 years of age should not use this medicine.
- This medicine can cause dependence and misuse; taking too much can be deadly.
Show 4 more warnings
- Do not break, chew, crush, or dissolve tablets; this can cause a fatal overdose.
- Avoid alcohol and grapefruit juice during treatment, as they can increase side effects.
- Do not take with MAO inhibitors (a type of antidepressant) or within 2 weeks of using them.
- Be careful when taking with other medicines that slow brain function (like sedatives or some antidepressants) as this can lead to serious breathing problems or coma.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Sedative. Reduce the dose already in mild renal impairment. Increases the risk of confusion and falling. Need for laxative is often necessary. Consider potential interactions. Avoid grapefruit. (updated 24.3.2025)