Oradexon

Oradexon is a corticosteroid that helps reduce inflammation and treats various inflammatory and immune system diseases.

Form
injektioneste, liuos
Strength
5 mg/ml
Active Ingredient
Dexamethasone sodium phosphate
Manufacturer
Aspen Pharma Trading Limited

How to Use

Dosage

For adults, the usual dose is 0.5-24 mg daily. For children, it's 0.2-0.4 mg/kg daily. For COVID-19, adults and teens (12 years or older and at least 40 kg) take 7.89 mg into a vein once daily for up to 10 days.

Method

A doctor will usually give you this medicine as a shot into a muscle, under your skin, or into a vein.

Important

Your doctor will decide your maximum daily dose. For adults, it's usually up to 24 mg. For COVID-19, treatment lasts up to 10 days.

Possible Side Effects

COMMON
  • Feeling depressed, including thoughts of suicide
  • Feeling very high (mania) or mood swings
  • Feeling anxious, trouble sleeping
  • Difficulty thinking, confusion, memory loss
  • Feeling, seeing, or hearing things that aren't real
  • Strange, frightening thoughts, behavioral changes, feeling alone
  • Skin rash, itching
  • Breathing difficulties, fainting
  • Swelling of face, lips, tongue, and/or throat (angioedema)
  • Stomach ulcers (may burst or bleed), indigestion, diarrhea, feeling sick or vomiting
  • Too much sodium or too little potassium or calcium in blood, fluid retention
  • High blood pressure
  • Thinning of bones (osteoporosis), increased fracture risk, bone disease
  • Slower wound healing, bruising, acne, increased sweating
  • Burning, redness, and swelling at injection site
  • Increased eye pressure (glaucoma), cataracts, eye infections, blurred or lost vision
  • Irregular or missed periods
  • Slow growth in children and teens
  • Facial swelling ('moon face')
  • Effects on diabetes, needing more diabetes medication
  • Body not responding normally to strong stress (accidents, surgery, illness)
  • Increased appetite, weight gain
  • Insomnia
  • Headache, vision problems (including eye pain or swelling)
  • Increased white blood cells in blood
RARE
  • Pancreatitis
  • Thickening of heart muscle in premature babies (usually resolves after treatment)
  • Blood clots
  • Tendon damage at injection site, or general tendon damage
  • Recurring infections that worsen (e.g., chickenpox, yeast infections)
  • Excess body hair growth (especially in women)
  • Worsening seizures or epilepsy
  • Severe, unusual headache with vision problems
  • Worsening of schizophrenia

Important Warnings

  • Do not take this medicine if you are allergic to dexamethasone or any of its ingredients.
  • Avoid this medicine if you have an infection affecting your whole body or a joint infection, or if your joints are unstable.
  • Tell your doctor if you have had allergic reactions to steroid medicines before.
  • Get urgent medical help if you get a headache, sweat a lot, have a fast heartbeat, or high blood pressure, as these can be signs of a serious tumor.
  • Inform your doctor if you have blood cancer and symptoms like muscle cramps, weakness, confusion, or trouble seeing or breathing.
Show 7 more warnings
  • Talk to your doctor if you have kidney or liver problems, high blood pressure, heart disease, diabetes, bone thinning (osteoporosis), or have experienced muscle weakness from steroids.
  • Let your doctor know if you have high eye pressure (glaucoma), a stomach ulcer, epilepsy, migraines, or a parasitic infection.
  • Tell your doctor if you have mental health problems, or if this medicine makes them worse (like mood changes, anxiety, or seeing things that aren't there).
  • Inform your doctor if you have tuberculosis, slow growth, Cushing's syndrome, a head injury, or have had a stroke.
  • Do not get any vaccines without talking to your doctor. Avoid people with chickenpox or measles if you haven't had them before.
  • Contact your doctor if your vision becomes blurry or you have other eye problems.
  • If this medicine is given to premature babies, their heart must be carefully monitored.

Use in Elderly Patients

Category C

Suitable for older adults, with specific precautions. Consider the risk of adverse effects of cortisone treatment. (updated 10.11.2025)